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Defining spasticity: a new approach considering current movement disorders terminology and botulinum toxin therapy

  • Dirk Dressler
    ,
  • Roongroj Bhidayasiri
    ,
  • Saeed Bohlega
    ,
  • Pedro Chana
    ,
  • Hsin Fen Chien
    ,
  • Tae Mo Chung
  • Hannover Medical School
    ,
  • Chulalongkorn University
    ,
  • Alfaisal University
    ,
  • Universidad de Santiago de Chile
    ,
  • Universidade de Sao Paulo - USP
    ,
  • Azienda Ospedaliera S. Maria di Terni
Research Output:
Contribution to journal
Article
Peer-review

Publication metrics

Metrics

SciVal
FWCI
2.11
SciVal
Author count
25
SciVal
Citations
90
SciVal
Paper percentile
88
Scopus
Citations

Abstract

Spasticity is a symptom occurring in many neurological conditions including stroke, multiple sclerosis, hypoxic brain damage, traumatic brain injury, tumours and heredodegenerative diseases. It affects large numbers of patients and may cause major disability. So far, spasticity has merely been described as part of the upper motor neurone syndrome or defined in a narrowed neurophysiological sense. This consensus organised by IAB—Interdisciplinary Working Group Movement Disorders wants to provide a brief and practical new definition of spasticity—for the first time—based on its various forms of muscle hyperactivity as described in the current movement disorders terminology. We propose the following new definition system: Spasticity describes involuntary muscle hyperactivity in the presence of central paresis. The involuntary muscle hyperactivity can consist of various forms of muscle hyperactivity: spasticity sensu strictu describes involuntary muscle hyperactivity triggered by rapid passive joint movements, rigidity involuntary muscle hyperactivity triggered by slow passive joint movements, dystonia spontaneous involuntary muscle hyperactivity and spasms complex involuntary movements usually triggered by sensory or acoustic stimuli. Spasticity can be described by a documentation system grouped along clinical picture (axis 1), aetiology (axis 2), localisation (axis 3) and additional central nervous system deficits (axis 4). Our new definition allows distinction of spasticity components accessible to BT therapy and those inaccessible. The documentation sheet presented provides essential information for planning of BT therapy.

Publication Information

Output type

Research Output:
Contribution to journal
Article
Peer-review

Original language

English

Pages from-to (Number of pages)

Pages 856-862 (7 pages)

Journal (Volume, Issue Number)

Deutsche Zeitschrift fur Nervenheilkunde (Volume 265, Issue 4)

Publication milestones

  • Published - 01/04/2018

Publication status

Published - 01/04/2018

ISSN

0340-5354

Publication IDs

  • Scopus: 85041495380
  • WOS: 000428928200013

Funding Details

FundersFunding numbers
Allergan and Merz Pharma
-
CU-CLUSTER fund of Chulalong-korn University
-
BMS
-
Pfizer
-
Allergan
-
Bayer Vital
-
Merz Pharmaceuticals
-
Ipsen
-
DSE
-