Wide association study of radiological features that predict future knee OA pain: Data from the OAI

Jorge I. Galván-Tejada, José M. Celaya-Padilla, Antonio Martínez-Torteya, Juan Rodriguez-Rojas, Víctor Treviño, José G. Tamez-Peña

Resultado de la investigación

4 Citas (Scopus)

Resumen

Knee pain is a common and one of the most important symptoms in Osteoarthritis (OA), and due to its nature it is a debilitating feature of OA. However, joint pain is a late manifestation of this illness. But, in early stages of the disease, changes in joint structures can be observed, some of the most common being: formation of bony osteophytes, cartilage degradation and joint space reduction. Given that these characteristics are early symptoms of radiological OA, this study aimed to achieve an association between these radiological features and joint pain caused by OA. Using public data from the Osteoarthritis Initiative (OAI), a case-control study was performed, where a multivariate feature selection algorithm was used to determine a relationship between future joint pain and the radiological evidence of the disease. Subjects showing no evidence of pain at their baseline visit, no medication for pain, and no symptomatic status, were included in this study. Those who developed pain at a posterior time point were considered as cases, the rest as controls. Radiological information was evaluated using two different scores, one quantitative and one semi-quantitative, both assessed by OAI radiologist groups. The obtained models suggest that early joint structure changes can be associated with future joint pain. An image based biomarker that could predict future pain, measured in early OA stages, could become a useful tool to improve the quality of life of people dealing OA. © 2014 SPIE.
Idioma originalEnglish
DOI
EstadoPublished - 1 ene 2014
Publicado de forma externa
EventoProgress in Biomedical Optics and Imaging - Proceedings of SPIE -
Duración: 1 ene 2014 → …

Conference

ConferenceProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Período1/1/14 → …

Huella dactilar

pain
Knee Osteoarthritis
Osteoarthritis
Association reactions
Pain
Arthralgia
Cartilage
Biomarkers
Feature extraction
Degradation
Joints
Osteophyte
cartilage
biomarkers
Case-Control Studies
Knee
Quality of Life
degradation

All Science Journal Classification (ASJC) codes

  • Electronic, Optical and Magnetic Materials
  • Atomic and Molecular Physics, and Optics
  • Biomaterials
  • Radiology Nuclear Medicine and imaging

Citar esto

Galván-Tejada, J. I., Celaya-Padilla, J. M., Martínez-Torteya, A., Rodriguez-Rojas, J., Treviño, V., & Tamez-Peña, J. G. (2014). Wide association study of radiological features that predict future knee OA pain: Data from the OAI. Papel presentado en Progress in Biomedical Optics and Imaging - Proceedings of SPIE, . https://doi.org/10.1117/12.2043859
Galván-Tejada, Jorge I. ; Celaya-Padilla, José M. ; Martínez-Torteya, Antonio ; Rodriguez-Rojas, Juan ; Treviño, Víctor ; Tamez-Peña, José G. / Wide association study of radiological features that predict future knee OA pain: Data from the OAI. Papel presentado en Progress in Biomedical Optics and Imaging - Proceedings of SPIE, .
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abstract = "Knee pain is a common and one of the most important symptoms in Osteoarthritis (OA), and due to its nature it is a debilitating feature of OA. However, joint pain is a late manifestation of this illness. But, in early stages of the disease, changes in joint structures can be observed, some of the most common being: formation of bony osteophytes, cartilage degradation and joint space reduction. Given that these characteristics are early symptoms of radiological OA, this study aimed to achieve an association between these radiological features and joint pain caused by OA. Using public data from the Osteoarthritis Initiative (OAI), a case-control study was performed, where a multivariate feature selection algorithm was used to determine a relationship between future joint pain and the radiological evidence of the disease. Subjects showing no evidence of pain at their baseline visit, no medication for pain, and no symptomatic status, were included in this study. Those who developed pain at a posterior time point were considered as cases, the rest as controls. Radiological information was evaluated using two different scores, one quantitative and one semi-quantitative, both assessed by OAI radiologist groups. The obtained models suggest that early joint structure changes can be associated with future joint pain. An image based biomarker that could predict future pain, measured in early OA stages, could become a useful tool to improve the quality of life of people dealing OA. {\circledC} 2014 SPIE.",
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Galván-Tejada, JI, Celaya-Padilla, JM, Martínez-Torteya, A, Rodriguez-Rojas, J, Treviño, V & Tamez-Peña, JG 2014, 'Wide association study of radiological features that predict future knee OA pain: Data from the OAI' Papel presentado en, 1/1/14, . https://doi.org/10.1117/12.2043859

Wide association study of radiological features that predict future knee OA pain: Data from the OAI. / Galván-Tejada, Jorge I.; Celaya-Padilla, José M.; Martínez-Torteya, Antonio; Rodriguez-Rojas, Juan; Treviño, Víctor; Tamez-Peña, José G.

2014. Papel presentado en Progress in Biomedical Optics and Imaging - Proceedings of SPIE, .

Resultado de la investigación

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AU - Galván-Tejada, Jorge I.

AU - Celaya-Padilla, José M.

AU - Martínez-Torteya, Antonio

AU - Rodriguez-Rojas, Juan

AU - Treviño, Víctor

AU - Tamez-Peña, José G.

PY - 2014/1/1

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N2 - Knee pain is a common and one of the most important symptoms in Osteoarthritis (OA), and due to its nature it is a debilitating feature of OA. However, joint pain is a late manifestation of this illness. But, in early stages of the disease, changes in joint structures can be observed, some of the most common being: formation of bony osteophytes, cartilage degradation and joint space reduction. Given that these characteristics are early symptoms of radiological OA, this study aimed to achieve an association between these radiological features and joint pain caused by OA. Using public data from the Osteoarthritis Initiative (OAI), a case-control study was performed, where a multivariate feature selection algorithm was used to determine a relationship between future joint pain and the radiological evidence of the disease. Subjects showing no evidence of pain at their baseline visit, no medication for pain, and no symptomatic status, were included in this study. Those who developed pain at a posterior time point were considered as cases, the rest as controls. Radiological information was evaluated using two different scores, one quantitative and one semi-quantitative, both assessed by OAI radiologist groups. The obtained models suggest that early joint structure changes can be associated with future joint pain. An image based biomarker that could predict future pain, measured in early OA stages, could become a useful tool to improve the quality of life of people dealing OA. © 2014 SPIE.

AB - Knee pain is a common and one of the most important symptoms in Osteoarthritis (OA), and due to its nature it is a debilitating feature of OA. However, joint pain is a late manifestation of this illness. But, in early stages of the disease, changes in joint structures can be observed, some of the most common being: formation of bony osteophytes, cartilage degradation and joint space reduction. Given that these characteristics are early symptoms of radiological OA, this study aimed to achieve an association between these radiological features and joint pain caused by OA. Using public data from the Osteoarthritis Initiative (OAI), a case-control study was performed, where a multivariate feature selection algorithm was used to determine a relationship between future joint pain and the radiological evidence of the disease. Subjects showing no evidence of pain at their baseline visit, no medication for pain, and no symptomatic status, were included in this study. Those who developed pain at a posterior time point were considered as cases, the rest as controls. Radiological information was evaluated using two different scores, one quantitative and one semi-quantitative, both assessed by OAI radiologist groups. The obtained models suggest that early joint structure changes can be associated with future joint pain. An image based biomarker that could predict future pain, measured in early OA stages, could become a useful tool to improve the quality of life of people dealing OA. © 2014 SPIE.

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Galván-Tejada JI, Celaya-Padilla JM, Martínez-Torteya A, Rodriguez-Rojas J, Treviño V, Tamez-Peña JG. Wide association study of radiological features that predict future knee OA pain: Data from the OAI. 2014. Papel presentado en Progress in Biomedical Optics and Imaging - Proceedings of SPIE, . https://doi.org/10.1117/12.2043859