Ten patients with superficial infantile hemangiomas were treated with imiquimod 5% cream for up to 16 weeks. Four patients achieved complete clinical resolution, 3 had excellent improvement, one showed moderate improvement, and one patient did not respond to therapy. Imiquimod may be an effective alternative for the treatment of superficial hemangiomas.
Welsh, O., Olazarán, Z., Gómez, M., Salas, J., & Berman, B. (2004). Treatment of infantile hemangiomas with short-term application of imiquimod 5% cream. Journal of the American Academy of Dermatology, 639-642. https://doi.org/10.1016/j.jaad.2004.04.022