TY - JOUR
T1 - Lepra
T2 - puesta al día. Definición, patogénesis, clasificación, diagnóstico y tratamiento
AU - Eichelmann, K.
AU - González González, S. E.
AU - Salas-Alanis, J. C.
AU - Ocampo-Candiani, J.
N1 - Copyright:
Copyright 2018 Elsevier B.V., All rights reserved.
PY - 2013/9/1
Y1 - 2013/9/1
N2 - Leprosy is a chronic granulomatous disease caused by the bacillus Mycobacterium leprae. It primarily affects the skin and peripheral nerves and is still endemic in various regions of the world. Clinical presentation depends on the patient's immune status at the time of infection and during the course of the disease. Leprosy is associated with disability and marginalization. Diagnosis is clinical and is made when the patient has at least 1 of the following cardinal signs specified by the World Health Organization: hypopigmented or erythematous macules with sensory loss; thickened peripheral nerves; or positive acid-fast skin smear or skin biopsy with loss of adnexa at affected sites. Leprosy is treated with a multidrug combination of rifampicin, clofazimine, and dapsone. Two main regimens are used depending on whether the patient has paucibacillary or multibacillary disease.
AB - Leprosy is a chronic granulomatous disease caused by the bacillus Mycobacterium leprae. It primarily affects the skin and peripheral nerves and is still endemic in various regions of the world. Clinical presentation depends on the patient's immune status at the time of infection and during the course of the disease. Leprosy is associated with disability and marginalization. Diagnosis is clinical and is made when the patient has at least 1 of the following cardinal signs specified by the World Health Organization: hypopigmented or erythematous macules with sensory loss; thickened peripheral nerves; or positive acid-fast skin smear or skin biopsy with loss of adnexa at affected sites. Leprosy is treated with a multidrug combination of rifampicin, clofazimine, and dapsone. Two main regimens are used depending on whether the patient has paucibacillary or multibacillary disease.
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UR - http://www.scopus.com/inward/citedby.url?scp=84883292553&partnerID=8YFLogxK
UR - https://www.mendeley.com/catalogue/17de66c8-eb65-39be-b2e5-87de8bdf7165/
U2 - 10.1016/j.ad.2012.03.003
DO - 10.1016/j.ad.2012.03.003
M3 - Short survey
SN - 0001-7310
VL - 104
SP - 554
EP - 563
JO - Actas Dermo-Sifiliograficas
JF - Actas Dermo-Sifiliograficas
IS - 7
ER -