ANALISIS DE LAS MANIFESTACIONES MORFOLOGICAS Y FUNCIONALES COMO RESULTADO DE LA IMPLEMENTACION DE UNA DIETA ALTA EN GRASA EN RATONES BALB-C

    Student thesis: Thesis

    Abstract

    Excessive consumption of foods high in saturated and trans fat has been associated with the
    incidence of overweight and obesity, which in turn are associated with health problems such as
    dyslipidemia. The aim of the present study was to investigate the biochemical, cognitive and
    morphological effects of the high-fat diet. Twenty BALB/c mice were divided into two groups: control
    and treatment. For 7 weeks a pellet-based diet was administered to the control group while the
    experimental group was administered a HFD.
    Two bromatological tests were performed on the diet, as well as biochemical and cognitive
    tests on the rodents. After 7 weeks of treatment, the mice were sacrificed for subsequent
    morphological analysis of the heart, kidney, liver, adipose tissue and pancreas. In the liver, larger
    nuclei were found as well as increased spaces for the formation of fat around the cytoplasm, in the
    kidneys compact glomeruli were found and therefore infiltration within the glomeruli.
    There was no difference between the other tissues, all showed similarities between the control
    group and the treated group, as well as no significant differences between the biochemical analyses.
    Date of Award5 Dec 2023
    Original languageSpanish
    Awarding Institution
    • Universidad de Monterrey
    SupervisorMaría Guadalupe Moreno Treviño (Supervisor), Edith Espinosa Páez (Supervisor), Diana Laura Castillo Carranza (Supervisor), Nancy Celestino Buentello (Supervisor) & Adriana Damaris Salinas Villarreal (Supervisor)

    Keywords

    • Dieta alta en grasa
    • Efectos morfologicos
    • efectos bioquimicos
    • ratones BALB-C
    • adultos

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