ALOR PREDICTOR DE LA RELACIÓN NEUTRÓFILOS/LINFOCITOS Y PLAQUETAS/LINFOCITOS EN MORTALIDAD, REQUERIMIENTO DE INTUBACIÓN Y USO DE VASOPRESORES EN PACIENTES CON NEUMONÍA POR SARS-CoV-2

Student thesis: Specialization thesis

Abstract

Infections of the lower respiratory tract can develop into pneumonia; the pulmonary parenchyma presents clinical criteria such as fever, productive cough, pleuritic pain, as well as an infiltrate or consolidation image in the chest X-ray. It is important to classify the severity of the pathology in each patient in order to provide optimal and individualized treatment. Since December 2019, the disease caused by the COVID-19 virus has been an important viral pathogen, with more than 30 million cases and nearly one million deaths reported worldwide. The most severe form of presentation is pneumonia.
The neutrophil/lymphocyte ratio (NLR) and platelet/lymphocyte ratio (PLR) are biochemical parameters that translate systemic inflammation; they are widely available and can be obtained directly from a complete blood count. These biomarkers have been under discussion as predictors of inflammation.
A retrospective analytic-observational case-control study was performed to find whether there is a difference in neutrophil/lymphocyte ratio and platelet/lymphocyte ratio values between adult patients with higher morbidity secondary to SARS CoV-2 pneumonia versus those with lower complications. Subsequently, a predictive model and a scale was created looking for the best cut-off point to predict complications.
Date of Award2022
Original languageEnglish
Awarding Institution
  • Universidad de Monterrey

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