Update on Pediatric Sepsis in Mexico

Crisell Arely Donath Benitez, Estefanía Mattenberger-Cantú, Ricardo Salas-Flores, Guillermo Baudelio Gómez-Morales, Paola Alejandra Mártinez-Diaz, María Guadalupe Moreno-Treviño, Laura Elvira García-Tovar, Francisco González-Salazar

Research output: Contribution to journalArticlepeer-review

Abstract

The main objective of this work was to determine and update the causal agents’ antibiotic sensitivity and resistance patterns on pediatric sepsis in a population of northeast Mexico. It is a cross-sectional study showing the results of blood cultures of pediatric patients with a presumptive diagnosis of sepsis were reviewed according to the SOFA criteria during 2020 in a public hospital in Mexico. A total of 207 blood cultures were performed and analyzed. The main isolated microorganisms were Staphylococcus, followed by Klebsiella and Escherichia. Several microorganisms showed 100% of sensitivity to different antibiotics or antifungals, some of them include Vancomycin, Voriconazole, Meropenem, Ciprofloxacin, and Cefotaxime. Bacteria of genre Staphylococcus showed its highest sensitivity rate to Tigecycline with 63.3%. Too Staphylococcus showed the highest resistance rate to Oxacillin with 50%. Although the patterns of sepsis-causing germs are similar to those previously reported, the development of new drugs with greater efficacy is the main contribution.

Original languageEnglish
Pages (from-to)2333794X221118017
JournalGlobal Pediatric Health
Volume9
DOIs
Publication statusPublished - Jan 2022

Bibliographical note

Funding Information:
The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: This work wasn’t supported by any institution nor received any type of funding.

Publisher Copyright:
© The Author(s) 2022.

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