Sexually transmitted pathogens, coinfections and risk factors in patients attending obstetrics and gynecology clinics in Jalisco, Mexico

Néstor Casillas-Vega, Rayo Morfín-Otero, Santos García, Jorge Llaca-Díaz, Eduardo Rodríguez-Noriega, Adrián Camacho-Ortiz, Ma de la Merced Ayala-Castellanos, Soraya Mendoza-Olazarán, Samantha Flores-Treviño, Santiago Petersen-Morfín, Héctor J Maldonado-Garza, Francisco J Bosques-Padilla, Elvira Garza-González

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

OBJECTIVE: To determine the frequency of nine sexually transmitted pathogens, coinfections and risk factors in patients attending obstetrics and gynecology clinics in Jalisco, Mexico.

MATERIALS AND METHODS: Samples from 662 patients attending obstetrics and gynecology clinics were analyzed. Treponema pallidum, HIV, and HCV were detected by serology. HPV was detected by Polimerase Chain Reaction (PCR), and its genotype was determined by Restriction Fragment Length Polymorphism (RFLP). Trichomonas vaginalis, HSV-1, HSV-2, Mycoplasma genitalium, Neisseria gonorrhoeae and T. pallidum were detected by multiplex PCR.

RESULTS: By serology, HIV frequency was 6.8%, T. pallidum was 2.26%, and HCV was 0.15%. By PCR, HPV frequency was 13.9%, (more frequent genotype was 16, 33.7%), followed by T. vaginalis (14.2%), HSV-1 (8.5%), M. genitalium (2,41%), N. gonorrhoeae (2.11%), HSV-2 (1.8%), and T. pallidum (1.05%). Patients infected with T. vaginalis were more likely to have multiple coinfections (p = 0.01).

CONCLUSION: The frequency of HPV, HVS-1, HSV-2, M. genitalium and T. vaginalis was lower than that reported. However, a high frequency of HIV, T. pallidum, and N. gonorrhoeae was detected.

Original languageEnglish
Pages (from-to)437-445
Number of pages9
JournalSalud Publica de Mexico
Volume58
Issue number4
DOIs
Publication statusPublished - Aug 2016
Externally publishedYes

Fingerprint

Treponema pallidum
Trichomonas vaginalis
Mexico
Coinfection
Gynecology
Mycoplasma genitalium
Obstetrics
Human Herpesvirus 2
Neisseria gonorrhoeae
Human Herpesvirus 1
HIV
Serology
Genotype
Restriction Fragment Length Polymorphisms

All Science Journal Classification (ASJC) codes

  • Public Health, Environmental and Occupational Health

Cite this

Casillas-Vega, N., Morfín-Otero, R., García, S., Llaca-Díaz, J., Rodríguez-Noriega, E., Camacho-Ortiz, A., ... Garza-González, E. (2016). Sexually transmitted pathogens, coinfections and risk factors in patients attending obstetrics and gynecology clinics in Jalisco, Mexico. Salud Publica de Mexico, 58(4), 437-445. https://doi.org/10.21149/spm.v58i4.8024
Casillas-Vega, Néstor ; Morfín-Otero, Rayo ; García, Santos ; Llaca-Díaz, Jorge ; Rodríguez-Noriega, Eduardo ; Camacho-Ortiz, Adrián ; Ayala-Castellanos, Ma de la Merced ; Mendoza-Olazarán, Soraya ; Flores-Treviño, Samantha ; Petersen-Morfín, Santiago ; Maldonado-Garza, Héctor J ; Bosques-Padilla, Francisco J ; Garza-González, Elvira. / Sexually transmitted pathogens, coinfections and risk factors in patients attending obstetrics and gynecology clinics in Jalisco, Mexico. In: Salud Publica de Mexico. 2016 ; Vol. 58, No. 4. pp. 437-445.
@article{59edfd44e3874f47a41b3b3fe4189c41,
title = "Sexually transmitted pathogens, coinfections and risk factors in patients attending obstetrics and gynecology clinics in Jalisco, Mexico",
abstract = "OBJECTIVE: To determine the frequency of nine sexually transmitted pathogens, coinfections and risk factors in patients attending obstetrics and gynecology clinics in Jalisco, Mexico.MATERIALS AND METHODS: Samples from 662 patients attending obstetrics and gynecology clinics were analyzed. Treponema pallidum, HIV, and HCV were detected by serology. HPV was detected by Polimerase Chain Reaction (PCR), and its genotype was determined by Restriction Fragment Length Polymorphism (RFLP). Trichomonas vaginalis, HSV-1, HSV-2, Mycoplasma genitalium, Neisseria gonorrhoeae and T. pallidum were detected by multiplex PCR.RESULTS: By serology, HIV frequency was 6.8{\%}, T. pallidum was 2.26{\%}, and HCV was 0.15{\%}. By PCR, HPV frequency was 13.9{\%}, (more frequent genotype was 16, 33.7{\%}), followed by T. vaginalis (14.2{\%}), HSV-1 (8.5{\%}), M. genitalium (2,41{\%}), N. gonorrhoeae (2.11{\%}), HSV-2 (1.8{\%}), and T. pallidum (1.05{\%}). Patients infected with T. vaginalis were more likely to have multiple coinfections (p = 0.01).CONCLUSION: The frequency of HPV, HVS-1, HSV-2, M. genitalium and T. vaginalis was lower than that reported. However, a high frequency of HIV, T. pallidum, and N. gonorrhoeae was detected.",
author = "N{\'e}stor Casillas-Vega and Rayo Morf{\'i}n-Otero and Santos Garc{\'i}a and Jorge Llaca-D{\'i}az and Eduardo Rodr{\'i}guez-Noriega and Adri{\'a}n Camacho-Ortiz and Ayala-Castellanos, {Ma de la Merced} and Soraya Mendoza-Olazar{\'a}n and Samantha Flores-Trevi{\~n}o and Santiago Petersen-Morf{\'i}n and Maldonado-Garza, {H{\'e}ctor J} and Bosques-Padilla, {Francisco J} and Elvira Garza-Gonz{\'a}lez",
year = "2016",
month = "8",
doi = "10.21149/spm.v58i4.8024",
language = "English",
volume = "58",
pages = "437--445",
journal = "Salud Publica de Mexico",
issn = "0036-3634",
publisher = "Instituto Nacional de Salud Publica",
number = "4",

}

Casillas-Vega, N, Morfín-Otero, R, García, S, Llaca-Díaz, J, Rodríguez-Noriega, E, Camacho-Ortiz, A, Ayala-Castellanos, MDLM, Mendoza-Olazarán, S, Flores-Treviño, S, Petersen-Morfín, S, Maldonado-Garza, HJ, Bosques-Padilla, FJ & Garza-González, E 2016, 'Sexually transmitted pathogens, coinfections and risk factors in patients attending obstetrics and gynecology clinics in Jalisco, Mexico', Salud Publica de Mexico, vol. 58, no. 4, pp. 437-445. https://doi.org/10.21149/spm.v58i4.8024

Sexually transmitted pathogens, coinfections and risk factors in patients attending obstetrics and gynecology clinics in Jalisco, Mexico. / Casillas-Vega, Néstor; Morfín-Otero, Rayo; García, Santos; Llaca-Díaz, Jorge; Rodríguez-Noriega, Eduardo; Camacho-Ortiz, Adrián; Ayala-Castellanos, Ma de la Merced; Mendoza-Olazarán, Soraya; Flores-Treviño, Samantha; Petersen-Morfín, Santiago; Maldonado-Garza, Héctor J; Bosques-Padilla, Francisco J; Garza-González, Elvira.

In: Salud Publica de Mexico, Vol. 58, No. 4, 08.2016, p. 437-445.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Sexually transmitted pathogens, coinfections and risk factors in patients attending obstetrics and gynecology clinics in Jalisco, Mexico

AU - Casillas-Vega, Néstor

AU - Morfín-Otero, Rayo

AU - García, Santos

AU - Llaca-Díaz, Jorge

AU - Rodríguez-Noriega, Eduardo

AU - Camacho-Ortiz, Adrián

AU - Ayala-Castellanos, Ma de la Merced

AU - Mendoza-Olazarán, Soraya

AU - Flores-Treviño, Samantha

AU - Petersen-Morfín, Santiago

AU - Maldonado-Garza, Héctor J

AU - Bosques-Padilla, Francisco J

AU - Garza-González, Elvira

PY - 2016/8

Y1 - 2016/8

N2 - OBJECTIVE: To determine the frequency of nine sexually transmitted pathogens, coinfections and risk factors in patients attending obstetrics and gynecology clinics in Jalisco, Mexico.MATERIALS AND METHODS: Samples from 662 patients attending obstetrics and gynecology clinics were analyzed. Treponema pallidum, HIV, and HCV were detected by serology. HPV was detected by Polimerase Chain Reaction (PCR), and its genotype was determined by Restriction Fragment Length Polymorphism (RFLP). Trichomonas vaginalis, HSV-1, HSV-2, Mycoplasma genitalium, Neisseria gonorrhoeae and T. pallidum were detected by multiplex PCR.RESULTS: By serology, HIV frequency was 6.8%, T. pallidum was 2.26%, and HCV was 0.15%. By PCR, HPV frequency was 13.9%, (more frequent genotype was 16, 33.7%), followed by T. vaginalis (14.2%), HSV-1 (8.5%), M. genitalium (2,41%), N. gonorrhoeae (2.11%), HSV-2 (1.8%), and T. pallidum (1.05%). Patients infected with T. vaginalis were more likely to have multiple coinfections (p = 0.01).CONCLUSION: The frequency of HPV, HVS-1, HSV-2, M. genitalium and T. vaginalis was lower than that reported. However, a high frequency of HIV, T. pallidum, and N. gonorrhoeae was detected.

AB - OBJECTIVE: To determine the frequency of nine sexually transmitted pathogens, coinfections and risk factors in patients attending obstetrics and gynecology clinics in Jalisco, Mexico.MATERIALS AND METHODS: Samples from 662 patients attending obstetrics and gynecology clinics were analyzed. Treponema pallidum, HIV, and HCV were detected by serology. HPV was detected by Polimerase Chain Reaction (PCR), and its genotype was determined by Restriction Fragment Length Polymorphism (RFLP). Trichomonas vaginalis, HSV-1, HSV-2, Mycoplasma genitalium, Neisseria gonorrhoeae and T. pallidum were detected by multiplex PCR.RESULTS: By serology, HIV frequency was 6.8%, T. pallidum was 2.26%, and HCV was 0.15%. By PCR, HPV frequency was 13.9%, (more frequent genotype was 16, 33.7%), followed by T. vaginalis (14.2%), HSV-1 (8.5%), M. genitalium (2,41%), N. gonorrhoeae (2.11%), HSV-2 (1.8%), and T. pallidum (1.05%). Patients infected with T. vaginalis were more likely to have multiple coinfections (p = 0.01).CONCLUSION: The frequency of HPV, HVS-1, HSV-2, M. genitalium and T. vaginalis was lower than that reported. However, a high frequency of HIV, T. pallidum, and N. gonorrhoeae was detected.

UR - http://www.scopus.com/inward/record.url?scp=84992468351&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84992468351&partnerID=8YFLogxK

U2 - 10.21149/spm.v58i4.8024

DO - 10.21149/spm.v58i4.8024

M3 - Article

C2 - 27599076

VL - 58

SP - 437

EP - 445

JO - Salud Publica de Mexico

JF - Salud Publica de Mexico

SN - 0036-3634

IS - 4

ER -

Casillas-Vega N, Morfín-Otero R, García S, Llaca-Díaz J, Rodríguez-Noriega E, Camacho-Ortiz A et al. Sexually transmitted pathogens, coinfections and risk factors in patients attending obstetrics and gynecology clinics in Jalisco, Mexico. Salud Publica de Mexico. 2016 Aug;58(4):437-445. https://doi.org/10.21149/spm.v58i4.8024