Prevalence and 3-year persistence of human papillomavirus serotypes in asymptomatic patients in Northern Mexico

Oscar R. Fajardo-Ramírez, María C. Barboza-Cerda, Rocío Ortiz-López, Augusto Rojas-Martínez, María L. Garza-Rodríguez, Abel Sepúlveda-Flores, Juan F. González-Guerrero, Sofía Bernal-Silva, Ricardo M. Cerda-Flores, Itzel E. Calleja-Macías, Socorro Rodríguez-Flores, Esthela Sandoval-Guzmán, Teresa Plascencia-Solis, Patricia Pérez-Reyes, Jesús Z. Villarreal, Hugo A. Barrera-Saldaña

Research output: Contribution to journalArticlepeer-review

5 Citations (Scopus)

Abstract

Objective: To investigate clinical outcomes and 3-year persistence of human papillomavirus (HPV) infections among women in Mexico. Methods: A prospective study enrolled sexually active women attending primary healthcare clinics in metropolitan Monterrey, Mexico, between June 3 and August 30, 2002. Baseline data were collected and participants underwent HPV screening. Patients with HPV infections were asked to attend a repeat screening appointment after 3 years, when the same screening data were gathered. Descriptive analyses were performed and the prevalence of cervical lesions and viral infections were examined. Results: In total, 1188 patients who underwent initial HPV screening were included. Cervical lesions were detected in 5 (0.4%) patients and 239 (20.1%) patients had HPV infections; 129 (54.0%) of these patients attended 3-year follow-up. Among the 357 HPV serotypes identified, the most prevalent serotypes were HPV-59, HPV-52, HPV-16, and HPV-56, detected 62 (17.4%), 38 (10.6%), 27 (7.6%), and 18 (5.0%) times, respectively. Of the 129 patients attending 3-year follow-up, 104 (80.6%) were clear from HPV infections, 13 (10.1%) patients had persistent HPV infections, and 12 (9.3%) had HPV infections with different HPV types. Conclusions: The HPV prevalence was 20.1% in the present study; the most prevalent infections were HPV-59, HPV-52, HPV-16, and HPV-56. At 3-year follow-up, 25 (19.4%) patients had HPV infections.

Original languageEnglish
Pages (from-to)40-46
Number of pages7
JournalInternational Journal of Gynecology and Obstetrics
Volume136
Issue number1
DOIs
Publication statusPublished - 3 Nov 2016
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Obstetrics and Gynaecology

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