TY - JOUR
T1 - Prevalence and 3-year persistence of human papillomavirus serotypes in asymptomatic patients in Northern Mexico
AU - Fajardo-Ramírez, Oscar R.
AU - Barboza-Cerda, María C.
AU - Ortiz-López, Rocío
AU - Rojas-Martínez, Augusto
AU - Garza-Rodríguez, María L.
AU - Sepúlveda-Flores, Abel
AU - González-Guerrero, Juan F.
AU - Bernal-Silva, Sofía
AU - Cerda-Flores, Ricardo M.
AU - Calleja-Macías, Itzel E.
AU - Rodríguez-Flores, Socorro
AU - Sandoval-Guzmán, Esthela
AU - Plascencia-Solis, Teresa
AU - Pérez-Reyes, Patricia
AU - Villarreal, Jesús Z.
AU - Barrera-Saldaña, Hugo A.
PY - 2016/11/3
Y1 - 2016/11/3
N2 - Objective: To investigate clinical outcomes and 3-year persistence of human papillomavirus (HPV) infections among women in Mexico. Methods: A prospective study enrolled sexually active women attending primary healthcare clinics in metropolitan Monterrey, Mexico, between June 3 and August 30, 2002. Baseline data were collected and participants underwent HPV screening. Patients with HPV infections were asked to attend a repeat screening appointment after 3 years, when the same screening data were gathered. Descriptive analyses were performed and the prevalence of cervical lesions and viral infections were examined. Results: In total, 1188 patients who underwent initial HPV screening were included. Cervical lesions were detected in 5 (0.4%) patients and 239 (20.1%) patients had HPV infections; 129 (54.0%) of these patients attended 3-year follow-up. Among the 357 HPV serotypes identified, the most prevalent serotypes were HPV-59, HPV-52, HPV-16, and HPV-56, detected 62 (17.4%), 38 (10.6%), 27 (7.6%), and 18 (5.0%) times, respectively. Of the 129 patients attending 3-year follow-up, 104 (80.6%) were clear from HPV infections, 13 (10.1%) patients had persistent HPV infections, and 12 (9.3%) had HPV infections with different HPV types. Conclusions: The HPV prevalence was 20.1% in the present study; the most prevalent infections were HPV-59, HPV-52, HPV-16, and HPV-56. At 3-year follow-up, 25 (19.4%) patients had HPV infections.
AB - Objective: To investigate clinical outcomes and 3-year persistence of human papillomavirus (HPV) infections among women in Mexico. Methods: A prospective study enrolled sexually active women attending primary healthcare clinics in metropolitan Monterrey, Mexico, between June 3 and August 30, 2002. Baseline data were collected and participants underwent HPV screening. Patients with HPV infections were asked to attend a repeat screening appointment after 3 years, when the same screening data were gathered. Descriptive analyses were performed and the prevalence of cervical lesions and viral infections were examined. Results: In total, 1188 patients who underwent initial HPV screening were included. Cervical lesions were detected in 5 (0.4%) patients and 239 (20.1%) patients had HPV infections; 129 (54.0%) of these patients attended 3-year follow-up. Among the 357 HPV serotypes identified, the most prevalent serotypes were HPV-59, HPV-52, HPV-16, and HPV-56, detected 62 (17.4%), 38 (10.6%), 27 (7.6%), and 18 (5.0%) times, respectively. Of the 129 patients attending 3-year follow-up, 104 (80.6%) were clear from HPV infections, 13 (10.1%) patients had persistent HPV infections, and 12 (9.3%) had HPV infections with different HPV types. Conclusions: The HPV prevalence was 20.1% in the present study; the most prevalent infections were HPV-59, HPV-52, HPV-16, and HPV-56. At 3-year follow-up, 25 (19.4%) patients had HPV infections.
UR - http://www.scopus.com/inward/record.url?scp=85020374915&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85020374915&partnerID=8YFLogxK
U2 - 10.1002/ijgo.12009
DO - 10.1002/ijgo.12009
M3 - Article
SN - 0020-7292
VL - 136
SP - 40
EP - 46
JO - International Journal of Gynecology and Obstetrics
JF - International Journal of Gynecology and Obstetrics
IS - 1
ER -
