Prevalence and 3-year persistence of human papillomavirus serotypes in asymptomatic patients in Northern Mexico

Oscar R. Fajardo-Ramírez, María C. Barboza-Cerda, Rocío Ortiz-López, Augusto Rojas-Martínez, María L. Garza-Rodríguez, Abel Sepúlveda-Flores, Juan F. González-Guerrero, Sofía Bernal-Silva, Ricardo M. Cerda-Flores, Itzel E. Calleja-Macías, Socorro Rodríguez-Flores, Esthela Sandoval-Guzmán, Teresa Plascencia-Solis, Patricia Pérez-Reyes, Jesús Z. Villarreal, Hugo A. Barrera-Saldaña

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Objective: To investigate clinical outcomes and 3-year persistence of human papillomavirus (HPV) infections among women in Mexico. Methods: A prospective study enrolled sexually active women attending primary healthcare clinics in metropolitan Monterrey, Mexico, between June 3 and August 30, 2002. Baseline data were collected and participants underwent HPV screening. Patients with HPV infections were asked to attend a repeat screening appointment after 3 years, when the same screening data were gathered. Descriptive analyses were performed and the prevalence of cervical lesions and viral infections were examined. Results: In total, 1188 patients who underwent initial HPV screening were included. Cervical lesions were detected in 5 (0.4%) patients and 239 (20.1%) patients had HPV infections; 129 (54.0%) of these patients attended 3-year follow-up. Among the 357 HPV serotypes identified, the most prevalent serotypes were HPV-59, HPV-52, HPV-16, and HPV-56, detected 62 (17.4%), 38 (10.6%), 27 (7.6%), and 18 (5.0%) times, respectively. Of the 129 patients attending 3-year follow-up, 104 (80.6%) were clear from HPV infections, 13 (10.1%) patients had persistent HPV infections, and 12 (9.3%) had HPV infections with different HPV types. Conclusions: The HPV prevalence was 20.1% in the present study; the most prevalent infections were HPV-59, HPV-52, HPV-16, and HPV-56. At 3-year follow-up, 25 (19.4%) patients had HPV infections.

Original languageEnglish
Pages (from-to)40-46
Number of pages7
JournalInternational Journal of Gynecology and Obstetrics
Volume136
Issue number1
DOIs
Publication statusPublished - 3 Nov 2016
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Obstetrics and Gynaecology

Cite this

Fajardo-Ramírez, O. R., Barboza-Cerda, M. C., Ortiz-López, R., Rojas-Martínez, A., Garza-Rodríguez, M. L., Sepúlveda-Flores, A., ... Barrera-Saldaña, H. A. (2016). Prevalence and 3-year persistence of human papillomavirus serotypes in asymptomatic patients in Northern Mexico. International Journal of Gynecology and Obstetrics, 136(1), 40-46. https://doi.org/10.1002/ijgo.12009
Fajardo-Ramírez, Oscar R. ; Barboza-Cerda, María C. ; Ortiz-López, Rocío ; Rojas-Martínez, Augusto ; Garza-Rodríguez, María L. ; Sepúlveda-Flores, Abel ; González-Guerrero, Juan F. ; Bernal-Silva, Sofía ; Cerda-Flores, Ricardo M. ; Calleja-Macías, Itzel E. ; Rodríguez-Flores, Socorro ; Sandoval-Guzmán, Esthela ; Plascencia-Solis, Teresa ; Pérez-Reyes, Patricia ; Villarreal, Jesús Z. ; Barrera-Saldaña, Hugo A. / Prevalence and 3-year persistence of human papillomavirus serotypes in asymptomatic patients in Northern Mexico. In: International Journal of Gynecology and Obstetrics. 2016 ; Vol. 136, No. 1. pp. 40-46.
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abstract = "Objective: To investigate clinical outcomes and 3-year persistence of human papillomavirus (HPV) infections among women in Mexico. Methods: A prospective study enrolled sexually active women attending primary healthcare clinics in metropolitan Monterrey, Mexico, between June 3 and August 30, 2002. Baseline data were collected and participants underwent HPV screening. Patients with HPV infections were asked to attend a repeat screening appointment after 3 years, when the same screening data were gathered. Descriptive analyses were performed and the prevalence of cervical lesions and viral infections were examined. Results: In total, 1188 patients who underwent initial HPV screening were included. Cervical lesions were detected in 5 (0.4{\%}) patients and 239 (20.1{\%}) patients had HPV infections; 129 (54.0{\%}) of these patients attended 3-year follow-up. Among the 357 HPV serotypes identified, the most prevalent serotypes were HPV-59, HPV-52, HPV-16, and HPV-56, detected 62 (17.4{\%}), 38 (10.6{\%}), 27 (7.6{\%}), and 18 (5.0{\%}) times, respectively. Of the 129 patients attending 3-year follow-up, 104 (80.6{\%}) were clear from HPV infections, 13 (10.1{\%}) patients had persistent HPV infections, and 12 (9.3{\%}) had HPV infections with different HPV types. Conclusions: The HPV prevalence was 20.1{\%} in the present study; the most prevalent infections were HPV-59, HPV-52, HPV-16, and HPV-56. At 3-year follow-up, 25 (19.4{\%}) patients had HPV infections.",
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Fajardo-Ramírez, OR, Barboza-Cerda, MC, Ortiz-López, R, Rojas-Martínez, A, Garza-Rodríguez, ML, Sepúlveda-Flores, A, González-Guerrero, JF, Bernal-Silva, S, Cerda-Flores, RM, Calleja-Macías, IE, Rodríguez-Flores, S, Sandoval-Guzmán, E, Plascencia-Solis, T, Pérez-Reyes, P, Villarreal, JZ & Barrera-Saldaña, HA 2016, 'Prevalence and 3-year persistence of human papillomavirus serotypes in asymptomatic patients in Northern Mexico', International Journal of Gynecology and Obstetrics, vol. 136, no. 1, pp. 40-46. https://doi.org/10.1002/ijgo.12009

Prevalence and 3-year persistence of human papillomavirus serotypes in asymptomatic patients in Northern Mexico. / Fajardo-Ramírez, Oscar R.; Barboza-Cerda, María C.; Ortiz-López, Rocío; Rojas-Martínez, Augusto; Garza-Rodríguez, María L.; Sepúlveda-Flores, Abel; González-Guerrero, Juan F.; Bernal-Silva, Sofía; Cerda-Flores, Ricardo M.; Calleja-Macías, Itzel E.; Rodríguez-Flores, Socorro; Sandoval-Guzmán, Esthela; Plascencia-Solis, Teresa; Pérez-Reyes, Patricia; Villarreal, Jesús Z.; Barrera-Saldaña, Hugo A.

In: International Journal of Gynecology and Obstetrics, Vol. 136, No. 1, 03.11.2016, p. 40-46.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Prevalence and 3-year persistence of human papillomavirus serotypes in asymptomatic patients in Northern Mexico

AU - Fajardo-Ramírez, Oscar R.

AU - Barboza-Cerda, María C.

AU - Ortiz-López, Rocío

AU - Rojas-Martínez, Augusto

AU - Garza-Rodríguez, María L.

AU - Sepúlveda-Flores, Abel

AU - González-Guerrero, Juan F.

AU - Bernal-Silva, Sofía

AU - Cerda-Flores, Ricardo M.

AU - Calleja-Macías, Itzel E.

AU - Rodríguez-Flores, Socorro

AU - Sandoval-Guzmán, Esthela

AU - Plascencia-Solis, Teresa

AU - Pérez-Reyes, Patricia

AU - Villarreal, Jesús Z.

AU - Barrera-Saldaña, Hugo A.

PY - 2016/11/3

Y1 - 2016/11/3

N2 - Objective: To investigate clinical outcomes and 3-year persistence of human papillomavirus (HPV) infections among women in Mexico. Methods: A prospective study enrolled sexually active women attending primary healthcare clinics in metropolitan Monterrey, Mexico, between June 3 and August 30, 2002. Baseline data were collected and participants underwent HPV screening. Patients with HPV infections were asked to attend a repeat screening appointment after 3 years, when the same screening data were gathered. Descriptive analyses were performed and the prevalence of cervical lesions and viral infections were examined. Results: In total, 1188 patients who underwent initial HPV screening were included. Cervical lesions were detected in 5 (0.4%) patients and 239 (20.1%) patients had HPV infections; 129 (54.0%) of these patients attended 3-year follow-up. Among the 357 HPV serotypes identified, the most prevalent serotypes were HPV-59, HPV-52, HPV-16, and HPV-56, detected 62 (17.4%), 38 (10.6%), 27 (7.6%), and 18 (5.0%) times, respectively. Of the 129 patients attending 3-year follow-up, 104 (80.6%) were clear from HPV infections, 13 (10.1%) patients had persistent HPV infections, and 12 (9.3%) had HPV infections with different HPV types. Conclusions: The HPV prevalence was 20.1% in the present study; the most prevalent infections were HPV-59, HPV-52, HPV-16, and HPV-56. At 3-year follow-up, 25 (19.4%) patients had HPV infections.

AB - Objective: To investigate clinical outcomes and 3-year persistence of human papillomavirus (HPV) infections among women in Mexico. Methods: A prospective study enrolled sexually active women attending primary healthcare clinics in metropolitan Monterrey, Mexico, between June 3 and August 30, 2002. Baseline data were collected and participants underwent HPV screening. Patients with HPV infections were asked to attend a repeat screening appointment after 3 years, when the same screening data were gathered. Descriptive analyses were performed and the prevalence of cervical lesions and viral infections were examined. Results: In total, 1188 patients who underwent initial HPV screening were included. Cervical lesions were detected in 5 (0.4%) patients and 239 (20.1%) patients had HPV infections; 129 (54.0%) of these patients attended 3-year follow-up. Among the 357 HPV serotypes identified, the most prevalent serotypes were HPV-59, HPV-52, HPV-16, and HPV-56, detected 62 (17.4%), 38 (10.6%), 27 (7.6%), and 18 (5.0%) times, respectively. Of the 129 patients attending 3-year follow-up, 104 (80.6%) were clear from HPV infections, 13 (10.1%) patients had persistent HPV infections, and 12 (9.3%) had HPV infections with different HPV types. Conclusions: The HPV prevalence was 20.1% in the present study; the most prevalent infections were HPV-59, HPV-52, HPV-16, and HPV-56. At 3-year follow-up, 25 (19.4%) patients had HPV infections.

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Fajardo-Ramírez OR, Barboza-Cerda MC, Ortiz-López R, Rojas-Martínez A, Garza-Rodríguez ML, Sepúlveda-Flores A et al. Prevalence and 3-year persistence of human papillomavirus serotypes in asymptomatic patients in Northern Mexico. International Journal of Gynecology and Obstetrics. 2016 Nov 3;136(1):40-46. https://doi.org/10.1002/ijgo.12009