Potential Production of Theranostic Boron Nitride Nanotubes (64Cu-BNNTs) Radiolabeled by Neutron Capture

Wellington Marcos Silva, Helio Ribeiro, Jaime Taha-Tijerina

Research output: Contribution to journalArticlepeer-review

Abstract

: In this work, the radioisotope 64Cu was obtained from copper (II) chloride dihydrate in a nuclear research reactor by neutron capture, (63Cu(n,γ)
64Cu), and incorporated into boron nitride nanotubes (BNNTs) using a solvothermal process. The produced 64Cu-BNNTs were analyzed by TEM,
MEV, FTIR, XDR, XPS and gamma spectrometry, with which it was possible to observe the formation of64Cu nanoparticles, with sizes of up to 16 nm, distributed through nanotubes. The synthesized of 64Cu nanostructures showed a pure photoemission peak of 511 keV, which is characteristic of gamma radiation. This type of emission is desirable for Photon Emission Tomography (PET scan) image acquisition, as well as its use in several cancer treatments. Thus, 64Cu-BNNTs present an excellent alternative as theranostic nanomaterials that can be used in diagnosis and therapy by different techniques used in nuclear medicine.
Original languageEnglish
Article number2907
Pages (from-to)2907
Number of pages13
JournalNanomaterials
Volume11
Issue number11
DOIs
Publication statusPublished - Nov 2021

Bibliographical note

Funding Information:
This research was funded by Mackenzie Research Fund (MackPesquisa, ProjectNo. 181009). Supported by the National Council for Scientific and Technological Development (CNPq), the Coordination ributions: W.M.S. and H.R. contributed to the conceptualization, methodology, measign, literature for literature for research, the Improvement project administration, of Higher Education data interpretation, Personnel?Brazil data (CAPES), analysis, valial analysis, and the Universidad de Monterrey. resources, investigation, figures, study design, supervision and writing. research, the Improvement project administration, of Higher Education data interpretation, Personnel?Brazil data (CAPES), analysis, valial analysis, and the Universidad de Monterrey. resources, investigation, figures, study design, supervision and writing.

Publisher Copyright:
© 2021 by the authors. Licensee MDPI, Basel, Switzerland.

All Science Journal Classification (ASJC) codes

  • Chemical Engineering(all)
  • Materials Science(all)

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