Photolyase Production and Current Applications: A Review

Diana Ramírez-Gamboa; Ana Laura Díaz-Zamorano; Edgar Ricardo Meléndez-Sánchez; Humberto Reyes-Pardo; Karen Rocio Villaseñor-Zepeda; Miguel E. López-Arellanes; Juan Eduardo Sosa-Hernández; Karina G. Coronado-Apodaca; Ana Gámez-Méndez; Samson Afewerki; Hafiz M.N. Iqbal; Roberto Parra-Saldivar; Manuel Martínez-Ruiz

doi:10.3390/molecules27185998

Photolyase Production and Current Applications: A Review

Diana Ramírez-Gamboa, Ana Laura Díaz-Zamorano, Edgar Ricardo Meléndez-Sánchez, Humberto Reyes-Pardo, Karen Rocio Villaseñor-Zepeda, Miguel E. López-Arellanes, Juan Eduardo Sosa-Hernández, Karina G. Coronado-Apodaca, Ana Gámez-Méndez, Samson Afewerki, Hafiz M.N. Iqbal, Roberto Parra-Saldivar^*, Manuel Martínez-Ruiz

^*Corresponding author for this work

Departamento Académico

Research output: Contribution to journal › Review article › peer-review

12 Citations (Scopus)

Abstract

The photolyase family consists of flavoproteins with enzyme activity able to repair ultraviolet light radiation damage by photoreactivation. DNA damage by the formation of a cyclobutane pyrimidine dimer (CPD) and a pyrimidine-pyrimidone (6-4) photoproduct can lead to multiple affections such as cellular apoptosis and mutagenesis that can evolve into skin cancer. The development of integrated applications to prevent the negative effects of prolonged sunlight exposure, usually during outdoor activities, is imperative. This study presents the functions, characteristics, and types of photolyases, their therapeutic and cosmetic applications, and additionally explores some photolyase-producing microorganisms and drug delivery systems.

Original language	English
Article number	5998
Journal	Molecules
Volume	27
Issue number	18
DOIs	https://doi.org/10.3390/molecules27185998
Publication status	Published - Sept 2022

Bibliographical note

Funding Information:
This work was also partially supported by Consejo Nacional de Ciencia y Tecnología (CONACYT) under Sistema Nacional de Investigadores (SNI) program awarded to Manuel Martínez Ruiz (CVU: 418151), Juan Eduardo Sosa-Hernández (CVU: 375202), Roberto Parra-Saldívar (CVU: 35753) and Hafiz M.N. Iqbal (CVU: 735340). Figures were created with BioRender.com.

Funding Information:
This research was supported by NET ZERO RESEARCH FUND (2021 call) from The Bank of Nova Scotia. The funding number is not applicable.

Publisher Copyright:
© 2022 by the authors.

All Science Journal Classification (ASJC) codes

Analytical Chemistry
Chemistry (miscellaneous)
Molecular Medicine
Pharmaceutical Science
Drug Discovery
Physical and Theoretical Chemistry
Organic Chemistry

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.3390/molecules27185998

Cite this

Ramírez-Gamboa, D., Díaz-Zamorano, A. L., Meléndez-Sánchez, E. R., Reyes-Pardo, H., Villaseñor-Zepeda, K. R., López-Arellanes, M. E., Sosa-Hernández, J. E., Coronado-Apodaca, K. G., Gámez-Méndez, A., Afewerki, S., Iqbal, H. M. N., Parra-Saldivar, R., & Martínez-Ruiz, M. (2022). Photolyase Production and Current Applications: A Review. Molecules, 27(18), Article 5998. https://doi.org/10.3390/molecules27185998

@article{02d3701dc51d47edbd591004f641e648,

title = "Photolyase Production and Current Applications: A Review",

abstract = "The photolyase family consists of flavoproteins with enzyme activity able to repair ultraviolet light radiation damage by photoreactivation. DNA damage by the formation of a cyclobutane pyrimidine dimer (CPD) and a pyrimidine-pyrimidone (6-4) photoproduct can lead to multiple affections such as cellular apoptosis and mutagenesis that can evolve into skin cancer. The development of integrated applications to prevent the negative effects of prolonged sunlight exposure, usually during outdoor activities, is imperative. This study presents the functions, characteristics, and types of photolyases, their therapeutic and cosmetic applications, and additionally explores some photolyase-producing microorganisms and drug delivery systems.",

author = "Diana Ram{\'i}rez-Gamboa and D{\'i}az-Zamorano, {Ana Laura} and Mel{\'e}ndez-S{\'a}nchez, {Edgar Ricardo} and Humberto Reyes-Pardo and Villase{\~n}or-Zepeda, {Karen Rocio} and L{\'o}pez-Arellanes, {Miguel E.} and Sosa-Hern{\'a}ndez, {Juan Eduardo} and Coronado-Apodaca, {Karina G.} and Ana G{\'a}mez-M{\'e}ndez and Samson Afewerki and Iqbal, {Hafiz M.N.} and Roberto Parra-Saldivar and Manuel Mart{\'i}nez-Ruiz",

note = "Funding Information: This work was also partially supported by Consejo Nacional de Ciencia y Tecnolog{\'i}a (CONACYT) under Sistema Nacional de Investigadores (SNI) program awarded to Manuel Mart{\'i}nez Ruiz (CVU: 418151), Juan Eduardo Sosa-Hern{\'a}ndez (CVU: 375202), Roberto Parra-Sald{\'i}var (CVU: 35753) and Hafiz M.N. Iqbal (CVU: 735340). Figures were created with BioRender.com. Funding Information: This research was supported by NET ZERO RESEARCH FUND (2021 call) from The Bank of Nova Scotia. The funding number is not applicable. Publisher Copyright: {\textcopyright} 2022 by the authors.",

year = "2022",

month = sep,

doi = "10.3390/molecules27185998",

language = "English",

volume = "27",

journal = "Molecules",

issn = "1420-3049",

publisher = "Multidisciplinary Digital Publishing Institute (MDPI)",

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Ramírez-Gamboa, D, Díaz-Zamorano, AL, Meléndez-Sánchez, ER, Reyes-Pardo, H, Villaseñor-Zepeda, KR, López-Arellanes, ME, Sosa-Hernández, JE, Coronado-Apodaca, KG, Gámez-Méndez, A, Afewerki, S, Iqbal, HMN, Parra-Saldivar, R & Martínez-Ruiz, M 2022, 'Photolyase Production and Current Applications: A Review', Molecules, vol. 27, no. 18, 5998. https://doi.org/10.3390/molecules27185998

TY - JOUR

T1 - Photolyase Production and Current Applications

T2 - A Review

AU - Ramírez-Gamboa, Diana

AU - Díaz-Zamorano, Ana Laura

AU - Meléndez-Sánchez, Edgar Ricardo

AU - Reyes-Pardo, Humberto

AU - Villaseñor-Zepeda, Karen Rocio

AU - López-Arellanes, Miguel E.

AU - Sosa-Hernández, Juan Eduardo

AU - Coronado-Apodaca, Karina G.

AU - Gámez-Méndez, Ana

AU - Afewerki, Samson

AU - Iqbal, Hafiz M.N.

AU - Parra-Saldivar, Roberto

AU - Martínez-Ruiz, Manuel

N1 - Funding Information: This work was also partially supported by Consejo Nacional de Ciencia y Tecnología (CONACYT) under Sistema Nacional de Investigadores (SNI) program awarded to Manuel Martínez Ruiz (CVU: 418151), Juan Eduardo Sosa-Hernández (CVU: 375202), Roberto Parra-Saldívar (CVU: 35753) and Hafiz M.N. Iqbal (CVU: 735340). Figures were created with BioRender.com. Funding Information: This research was supported by NET ZERO RESEARCH FUND (2021 call) from The Bank of Nova Scotia. The funding number is not applicable. Publisher Copyright: © 2022 by the authors.

PY - 2022/9

Y1 - 2022/9

N2 - The photolyase family consists of flavoproteins with enzyme activity able to repair ultraviolet light radiation damage by photoreactivation. DNA damage by the formation of a cyclobutane pyrimidine dimer (CPD) and a pyrimidine-pyrimidone (6-4) photoproduct can lead to multiple affections such as cellular apoptosis and mutagenesis that can evolve into skin cancer. The development of integrated applications to prevent the negative effects of prolonged sunlight exposure, usually during outdoor activities, is imperative. This study presents the functions, characteristics, and types of photolyases, their therapeutic and cosmetic applications, and additionally explores some photolyase-producing microorganisms and drug delivery systems.

AB - The photolyase family consists of flavoproteins with enzyme activity able to repair ultraviolet light radiation damage by photoreactivation. DNA damage by the formation of a cyclobutane pyrimidine dimer (CPD) and a pyrimidine-pyrimidone (6-4) photoproduct can lead to multiple affections such as cellular apoptosis and mutagenesis that can evolve into skin cancer. The development of integrated applications to prevent the negative effects of prolonged sunlight exposure, usually during outdoor activities, is imperative. This study presents the functions, characteristics, and types of photolyases, their therapeutic and cosmetic applications, and additionally explores some photolyase-producing microorganisms and drug delivery systems.

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DO - 10.3390/molecules27185998

M3 - Review article

C2 - 36144740

AN - SCOPUS:85138349014

SN - 1420-3049

VL - 27

JO - Molecules

JF - Molecules

IS - 18

M1 - 5998

ER -

Photolyase Production and Current Applications: A Review

Abstract

Bibliographical note

All Science Journal Classification (ASJC) codes

UN SDGs

Access to Document

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