Orexins are peptide neurotransmitters that regulate arousal and motivated behaviors such as feeding and mating. Decreased levels of orexins ara causally correlated with narcolepsy and their synthetic agonists can be used to treat this disorder and induce wakefulness. Orexins also participate in regulating addictive behaviors and modulation of the orexinergic system could be useful as a pharmacological target for drug addiction and obesity treatment.
|Translated title of the contribution||Orexin and its clinical applications|
|Number of pages||11|
|Publication status||Published - 30 Jan 2019|
All Science Journal Classification (ASJC) codes
- Biochemistry, Genetics and Molecular Biology (miscellaneous)