Inflammatory effect on the gastrointestinal system associated with COVID-19

Paulina Delgado-Gonzalez, Carlos A. Gonzalez-Villarreal, Jorge A. Roacho-Perez, Adriana G. Quiroz-Reyes, Jose Francisco Islas, Juan Luis Delgado-Gallegos, Daniel Arellanos-Soto, Kame A. Galan-Huerta, Elsa N. Garza-Treviño*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

11 Citations (Scopus)


The severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) that causes coronavirus disease-2019 (COVID-19) has provoked a global pandemic, mainly affecting the respiratory tract; however, a percentage of infected individuals can develop gastrointestinal (GI) symptoms. Some studies describe the development of GI symptoms and how they affect the progression of COVID-19. In this review, we summarize the main mechanisms associated with gut damage during infection by SARS-CoV-2 as well as other organs such as the liver and pancreas. Not only are host factors associated with severe COVID-19 but intestinal microbiota dysbiosis is also observed in patients with severe disease.

Original languageEnglish
Pages (from-to)4160-4171
Number of pages12
JournalWorld Journal of Gastroenterology
Issue number26
Publication statusPublished - 14 Jul 2021

Bibliographical note

Publisher Copyright:
© The Author(s) 2021.

All Science Journal Classification (ASJC) codes

  • Gastroenterology


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