Impact of daily chlorhexidine baths and hand hygiene compliance on nosocomial infection rates in critically ill patients

Michel Fernando Martínez-Reséndez, Elvira Garza-González, Soraya Mendoza-Olazaran, Alexis Herrera-Guerra, Juan Manuel Rodríguez-López, Edelmiro Pérez-Rodriguez, Roberto Mercado-Longoria, Adrián Camacho-Ortiz

Research output: Contribution to journalArticle

28 Citations (Scopus)

Abstract

BACKGROUND: Up to 25% of all nosocomial infections (NIs) develop in critically ill patients. Our objective was to evaluate chlorhexidine (CHX) bathing and hand hygiene (HH) compliance in the reduction of NIs in the intensive care unit.

METHODS: The study comprised three 6-month periods: preintervention (PIP; soap/water bathing), intervention (IP; bathing with CHX-impregnated wipes), and postintervention (PoIP; soap/water bathing). An HH program was implemented during the IP and PoIP. Primary outcomes were global and specific NI rates.

RESULTS: A total of 1007 patients were included. Infection rates per 100 discharges were higher in the PIP compared with the IP and also higher in the PoIP compared with the IP (P = .0004 and .0109, respectively). Global infection rates per 1000 hospital-days were higher in the PIP than in the IP (P = .0268). The rates of ventilator-associated pneumonia (VAP) and catheter-associated urinary tract infection (CAUTI) were higher in the PIP than in the IP (P = .036 and .0001, respectively). Isolation of Acinetobacter baumannii from VAP specimens (P = .0204) and isolation of Candida spp from CAUTI specimens (P = .0005) decreased as well.

CONCLUSION: The combined intervention reduced global and specific infection rates, including rates of VAP associated with A baumannii and CAUTI associated with Candida spp.

Original languageEnglish
Pages (from-to)713-7
Number of pages5
JournalAmerican Journal of Infection Control
Volume42
Issue number7
DOIs
Publication statusPublished - Jul 2014
Externally publishedYes

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Hand Hygiene
Ventilator-Associated Pneumonia
Catheter-Related Infections
Chlorhexidine
Cross Infection
Baths
Critical Illness
Urinary Tract Infections
Soaps
Candida
Infection
Acinetobacter baumannii
Water
Intensive Care Units

Bibliographical note

Copyright © 2014 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Mosby, Inc. All rights reserved.

Cite this

Martínez-Reséndez, M. F., Garza-González, E., Mendoza-Olazaran, S., Herrera-Guerra, A., Rodríguez-López, J. M., Pérez-Rodriguez, E., ... Camacho-Ortiz, A. (2014). Impact of daily chlorhexidine baths and hand hygiene compliance on nosocomial infection rates in critically ill patients. American Journal of Infection Control, 42(7), 713-7. https://doi.org/10.1016/j.ajic.2014.03.354
Martínez-Reséndez, Michel Fernando ; Garza-González, Elvira ; Mendoza-Olazaran, Soraya ; Herrera-Guerra, Alexis ; Rodríguez-López, Juan Manuel ; Pérez-Rodriguez, Edelmiro ; Mercado-Longoria, Roberto ; Camacho-Ortiz, Adrián. / Impact of daily chlorhexidine baths and hand hygiene compliance on nosocomial infection rates in critically ill patients. In: American Journal of Infection Control. 2014 ; Vol. 42, No. 7. pp. 713-7.
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abstract = "BACKGROUND: Up to 25{\%} of all nosocomial infections (NIs) develop in critically ill patients. Our objective was to evaluate chlorhexidine (CHX) bathing and hand hygiene (HH) compliance in the reduction of NIs in the intensive care unit.METHODS: The study comprised three 6-month periods: preintervention (PIP; soap/water bathing), intervention (IP; bathing with CHX-impregnated wipes), and postintervention (PoIP; soap/water bathing). An HH program was implemented during the IP and PoIP. Primary outcomes were global and specific NI rates.RESULTS: A total of 1007 patients were included. Infection rates per 100 discharges were higher in the PIP compared with the IP and also higher in the PoIP compared with the IP (P = .0004 and .0109, respectively). Global infection rates per 1000 hospital-days were higher in the PIP than in the IP (P = .0268). The rates of ventilator-associated pneumonia (VAP) and catheter-associated urinary tract infection (CAUTI) were higher in the PIP than in the IP (P = .036 and .0001, respectively). Isolation of Acinetobacter baumannii from VAP specimens (P = .0204) and isolation of Candida spp from CAUTI specimens (P = .0005) decreased as well.CONCLUSION: The combined intervention reduced global and specific infection rates, including rates of VAP associated with A baumannii and CAUTI associated with Candida spp.",
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Martínez-Reséndez, MF, Garza-González, E, Mendoza-Olazaran, S, Herrera-Guerra, A, Rodríguez-López, JM, Pérez-Rodriguez, E, Mercado-Longoria, R & Camacho-Ortiz, A 2014, 'Impact of daily chlorhexidine baths and hand hygiene compliance on nosocomial infection rates in critically ill patients', American Journal of Infection Control, vol. 42, no. 7, pp. 713-7. https://doi.org/10.1016/j.ajic.2014.03.354

Impact of daily chlorhexidine baths and hand hygiene compliance on nosocomial infection rates in critically ill patients. / Martínez-Reséndez, Michel Fernando; Garza-González, Elvira; Mendoza-Olazaran, Soraya; Herrera-Guerra, Alexis; Rodríguez-López, Juan Manuel; Pérez-Rodriguez, Edelmiro; Mercado-Longoria, Roberto; Camacho-Ortiz, Adrián.

In: American Journal of Infection Control, Vol. 42, No. 7, 07.2014, p. 713-7.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Impact of daily chlorhexidine baths and hand hygiene compliance on nosocomial infection rates in critically ill patients

AU - Martínez-Reséndez, Michel Fernando

AU - Garza-González, Elvira

AU - Mendoza-Olazaran, Soraya

AU - Herrera-Guerra, Alexis

AU - Rodríguez-López, Juan Manuel

AU - Pérez-Rodriguez, Edelmiro

AU - Mercado-Longoria, Roberto

AU - Camacho-Ortiz, Adrián

N1 - Copyright © 2014 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Mosby, Inc. All rights reserved.

PY - 2014/7

Y1 - 2014/7

N2 - BACKGROUND: Up to 25% of all nosocomial infections (NIs) develop in critically ill patients. Our objective was to evaluate chlorhexidine (CHX) bathing and hand hygiene (HH) compliance in the reduction of NIs in the intensive care unit.METHODS: The study comprised three 6-month periods: preintervention (PIP; soap/water bathing), intervention (IP; bathing with CHX-impregnated wipes), and postintervention (PoIP; soap/water bathing). An HH program was implemented during the IP and PoIP. Primary outcomes were global and specific NI rates.RESULTS: A total of 1007 patients were included. Infection rates per 100 discharges were higher in the PIP compared with the IP and also higher in the PoIP compared with the IP (P = .0004 and .0109, respectively). Global infection rates per 1000 hospital-days were higher in the PIP than in the IP (P = .0268). The rates of ventilator-associated pneumonia (VAP) and catheter-associated urinary tract infection (CAUTI) were higher in the PIP than in the IP (P = .036 and .0001, respectively). Isolation of Acinetobacter baumannii from VAP specimens (P = .0204) and isolation of Candida spp from CAUTI specimens (P = .0005) decreased as well.CONCLUSION: The combined intervention reduced global and specific infection rates, including rates of VAP associated with A baumannii and CAUTI associated with Candida spp.

AB - BACKGROUND: Up to 25% of all nosocomial infections (NIs) develop in critically ill patients. Our objective was to evaluate chlorhexidine (CHX) bathing and hand hygiene (HH) compliance in the reduction of NIs in the intensive care unit.METHODS: The study comprised three 6-month periods: preintervention (PIP; soap/water bathing), intervention (IP; bathing with CHX-impregnated wipes), and postintervention (PoIP; soap/water bathing). An HH program was implemented during the IP and PoIP. Primary outcomes were global and specific NI rates.RESULTS: A total of 1007 patients were included. Infection rates per 100 discharges were higher in the PIP compared with the IP and also higher in the PoIP compared with the IP (P = .0004 and .0109, respectively). Global infection rates per 1000 hospital-days were higher in the PIP than in the IP (P = .0268). The rates of ventilator-associated pneumonia (VAP) and catheter-associated urinary tract infection (CAUTI) were higher in the PIP than in the IP (P = .036 and .0001, respectively). Isolation of Acinetobacter baumannii from VAP specimens (P = .0204) and isolation of Candida spp from CAUTI specimens (P = .0005) decreased as well.CONCLUSION: The combined intervention reduced global and specific infection rates, including rates of VAP associated with A baumannii and CAUTI associated with Candida spp.

U2 - 10.1016/j.ajic.2014.03.354

DO - 10.1016/j.ajic.2014.03.354

M3 - Article

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VL - 42

SP - 713

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JO - American Journal of Infection Control

JF - American Journal of Infection Control

SN - 0196-6553

IS - 7

ER -