Exposure to intimate partner violence in utero and infant internalizing behaviors: Moderation by salivary cortisol-alpha amylase asymmetry

Cecilia Martinez-Torteya, G. Anne Bogat, Joseph S. Lonstein, Douglas A. Granger, Alytia A. Levendosky

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

© 2017 Guided by the main tenets of contemporary models of the developmental origins of health and disease, this study evaluated whether individual differences in reactivity of the hypothalamic-pituitary-adrenal (HPA) axis and Sympathetic Nervous System (SNS) moderate the effect of prenatal exposure to trauma on internalizing and externalizing behaviors during infancy. Participants were a community sample of 182 mothers (M age = 25 years, 43% Caucasian, 33% Black/African American, 24% Biracial/Other) and their infants (59% girls; M age = 11.8 months). Each mother completed questionnaires that assessed IPV experienced during pregnancy and also reported on her infant's behavior problems. Infant saliva samples (later assayed for cortisol and sAA) were collected before and after a frustrating task (i.e., arm restraint). Results revealed that the association between in utero IPV and infant internalizing behaviors was most pronounced for infants with asymmetrical HPA-SNS (i.e., high-cortisol and low-sAA) reactivity to frustration, and least pronounced for infants with symmetrical HPA-SNS (i.e., low-cortisol and low-sAA or high-cortisol and high-sAA) reactivity to frustration. Higher levels of externalizing behavior, in contrast, were associated with higher levels of prenatal IPV but unrelated to either cortisol or sAA reactivity to stress. Findings replicate documented associations between maternal IPV exposure during pregnancy and offspring risk. Moreover, findings advance our understanding of individual differences in the developmental origins of health and disease and provide additional evidence that assessing multiple stress biomarkers contributes to a more comprehensive understanding of individual vulnerability to adversity.
Original languageEnglish
Pages (from-to)40-48
Number of pages9
JournalEarly Human Development
DOIs
Publication statusPublished - 1 Oct 2017
Externally publishedYes

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Salivary alpha-Amylases
Infant Behavior
Hydrocortisone
Sympathetic Nervous System
Frustration
Individuality
Mothers
Maternal Exposure
Pregnancy
Health
Saliva
African Americans
Biomarkers
Exposure to Violence
Intimate Partner Violence
Wounds and Injuries

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health
  • Obstetrics and Gynaecology

Cite this

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title = "Exposure to intimate partner violence in utero and infant internalizing behaviors: Moderation by salivary cortisol-alpha amylase asymmetry",
abstract = "{\circledC} 2017 Guided by the main tenets of contemporary models of the developmental origins of health and disease, this study evaluated whether individual differences in reactivity of the hypothalamic-pituitary-adrenal (HPA) axis and Sympathetic Nervous System (SNS) moderate the effect of prenatal exposure to trauma on internalizing and externalizing behaviors during infancy. Participants were a community sample of 182 mothers (M age = 25 years, 43{\%} Caucasian, 33{\%} Black/African American, 24{\%} Biracial/Other) and their infants (59{\%} girls; M age = 11.8 months). Each mother completed questionnaires that assessed IPV experienced during pregnancy and also reported on her infant's behavior problems. Infant saliva samples (later assayed for cortisol and sAA) were collected before and after a frustrating task (i.e., arm restraint). Results revealed that the association between in utero IPV and infant internalizing behaviors was most pronounced for infants with asymmetrical HPA-SNS (i.e., high-cortisol and low-sAA) reactivity to frustration, and least pronounced for infants with symmetrical HPA-SNS (i.e., low-cortisol and low-sAA or high-cortisol and high-sAA) reactivity to frustration. Higher levels of externalizing behavior, in contrast, were associated with higher levels of prenatal IPV but unrelated to either cortisol or sAA reactivity to stress. Findings replicate documented associations between maternal IPV exposure during pregnancy and offspring risk. Moreover, findings advance our understanding of individual differences in the developmental origins of health and disease and provide additional evidence that assessing multiple stress biomarkers contributes to a more comprehensive understanding of individual vulnerability to adversity.",
author = "Cecilia Martinez-Torteya and Bogat, {G. Anne} and Lonstein, {Joseph S.} and Granger, {Douglas A.} and Levendosky, {Alytia A.}",
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Exposure to intimate partner violence in utero and infant internalizing behaviors: Moderation by salivary cortisol-alpha amylase asymmetry. / Martinez-Torteya, Cecilia; Bogat, G. Anne; Lonstein, Joseph S.; Granger, Douglas A.; Levendosky, Alytia A.

In: Early Human Development, 01.10.2017, p. 40-48.

Research output: Contribution to journalArticle

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AU - Martinez-Torteya, Cecilia

AU - Bogat, G. Anne

AU - Lonstein, Joseph S.

AU - Granger, Douglas A.

AU - Levendosky, Alytia A.

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