Effect of Digital-Tool-Supported Basal Insulin Titration Algorithm in Reaching Glycemic Control in Patients with Type 2 Diabetes in Mexico

Hector Eloy Tamez-Pérez, Oscar Manuel Cantú-Santos, Dalia Gutierrez-González, Rosalinda González-Facio, Maria Elena Romero-Ibarguengoitia

Research output: Contribution to journalArticlepeer-review

Abstract

Background: My Dose Coach (MDC) is a mobile application combined with a web portal that can suggest optimized basal insulin (BI) injection doses using Self-Measured Plasma Glucose (SMPG) and hypoglycemia data. This study aimed to evaluate its efficacy on patients reaching SMPG and Fasting blood glucose (FBG) target range 90-130 mg/dl (5-7.2 mmol/L) goals without severe hypoglycemic episodes. We also addressed the mean reduction in glycated hemoglobin (A1C), FBG, and SMPG and the improvement in the WHO’s Five Well Being Index (WBI). Methods: This prospective pilot study involved the use of MDC in outpatients with type 2 diabetes (T2DM) from a Hospital in Northern Mexico. Patients on treatment with any BI were included in the study. The follow-up was of 16 weeks. Student t-tests or McNemar test were used for effect comparisons. Results: We included 158 patients (46.8% women), mean (SD) age 51 (10.3) years. We achieved SMPG target range in 58.9% [mean (95CI) reduction of 30.9 mg/dl (22.5-37.7; P <.001)] of the patients [66(28) days], with no severe hypoglycemia events. FBG goal was reached in 55.7% [mean (95CI) reduction of 63.4 mg/dl (49.6-77.2; P <.001)]. The mean (95CI) reduction of A1C was 1.78% (1.47-2, P <.01) with the last observation carried forward. There was a mean (95CI) increase of 2.23 (−3, −1.4, P <.01) points in WBI scale. Conclusions: MDC successfully helped to achieve FBG and SMPG goals, reduced A1C, and increased WBI with no severe hypoglycemia events.

Original languageEnglish
JournalJournal of diabetes science and technology
DOIs
Publication statusPublished - 29 Jul 2021
Externally publishedYes

Bibliographical note

Funding Information:
The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: Sanofi Mexico provided My Dose Coach app and the glucometers for the patients. The rest of the research project was funded by the hospital’s private fundings. Sanofi Mexico suggested language polishing editor but had no role in data collection and analysis, decision to publish, or preparation of the manuscript.

Publisher Copyright:
© 2021 Diabetes Technology Society.

All Science Journal Classification (ASJC) codes

  • Internal Medicine
  • Endocrinology, Diabetes and Metabolism
  • Bioengineering
  • Biomedical Engineering

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