Diversity of Circulating Clostridioides difficile Ribotypes in Mexico and Susceptibility to Fidaxomicin, Vancomycin, and Metronidazole

Adrián Martínez-Meléndez, Laura Tijerina-Rodríguez, Nathania Collins, Simon D. Baines, Rayo Morfin-Otero, Adrián Camacho-Ortíz, Licet Villarreal-Treviño, Elvira Garza-González

Research output: Contribution to journalArticlepeer-review

Abstract

In this study, we report the results of the epidemiological analysis of Clostridioides difficile ribotypes (RTs) and antimicrobial susceptibility testing. Most isolates were RT027, representing 73% (84/115) of isolates. No isolates with reduced susceptibility to fidaxomicin were found; however, 38 (33.04%) isolates had reduced susceptibility to metronidazole, and 7 isolates (6.1%) had reduced susceptibility to vancomycin. These findings highlight the need for continuous surveillance of C. difficile RTs and antimicrobial susceptibility testing.

Original languageEnglish
Pages (from-to)1672-1676
Number of pages5
JournalMicrobial Drug Resistance
Volume27
Issue number12
DOIs
Publication statusPublished - Dec 2021
Externally publishedYes

Bibliographical note

Funding Information:
This work was funded by Consejo Nacional de Ciencia y Tecnología (Grant 284042).

Publisher Copyright:
© Copyright 2021, Mary Ann Liebert, Inc., publishers 2021.

All Science Journal Classification (ASJC) codes

  • Microbiology
  • Immunology
  • Pharmacology
  • Microbiology (medical)

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