Diversity of Circulating Clostridioides difficile Ribotypes in Mexico and Susceptibility to Fidaxomicin, Vancomycin, and Metronidazole

Adrián Martínez-Meléndez; Laura Tijerina-Rodríguez; Nathania Collins; Simon D. Baines; Rayo Morfin-Otero; Adrián Camacho-Ortíz; Licet Villarreal-Treviño; Elvira Garza-González

doi:10.1089/mdr.2020.0583

Diversity of Circulating Clostridioides difficile Ribotypes in Mexico and Susceptibility to Fidaxomicin, Vancomycin, and Metronidazole

Adrián Martínez-Meléndez, Laura Tijerina-Rodríguez, Nathania Collins, Simon D. Baines, Rayo Morfin-Otero, Adrián Camacho-Ortíz, Licet Villarreal-Treviño, Elvira Garza-González^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

Abstract

In this study, we report the results of the epidemiological analysis of Clostridioides difficile ribotypes (RTs) and antimicrobial susceptibility testing. Most isolates were RT027, representing 73% (84/115) of isolates. No isolates with reduced susceptibility to fidaxomicin were found; however, 38 (33.04%) isolates had reduced susceptibility to metronidazole, and 7 isolates (6.1%) had reduced susceptibility to vancomycin. These findings highlight the need for continuous surveillance of C. difficile RTs and antimicrobial susceptibility testing.

Original language	English
Pages (from-to)	1672-1676
Number of pages	5
Journal	Microbial Drug Resistance
Volume	27
Issue number	12
DOIs	https://doi.org/10.1089/mdr.2020.0583
Publication status	Published - Dec 2021
Externally published	Yes

Bibliographical note

Funding Information:
This work was funded by Consejo Nacional de Ciencia y Tecnología (Grant 284042).

Publisher Copyright:
© Copyright 2021, Mary Ann Liebert, Inc., publishers 2021.

All Science Journal Classification (ASJC) codes

Microbiology
Immunology
Pharmacology
Microbiology (medical)

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10.1089/mdr.2020.0583

Cite this

Martínez-Meléndez, A., Tijerina-Rodríguez, L., Collins, N., Baines, S. D., Morfin-Otero, R., Camacho-Ortíz, A., Villarreal-Treviño, L., & Garza-González, E. (2021). Diversity of Circulating Clostridioides difficile Ribotypes in Mexico and Susceptibility to Fidaxomicin, Vancomycin, and Metronidazole. Microbial Drug Resistance, 27(12), 1672-1676. https://doi.org/10.1089/mdr.2020.0583

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title = "Diversity of Circulating Clostridioides difficile Ribotypes in Mexico and Susceptibility to Fidaxomicin, Vancomycin, and Metronidazole",

abstract = "In this study, we report the results of the epidemiological analysis of Clostridioides difficile ribotypes (RTs) and antimicrobial susceptibility testing. Most isolates were RT027, representing 73% (84/115) of isolates. No isolates with reduced susceptibility to fidaxomicin were found; however, 38 (33.04%) isolates had reduced susceptibility to metronidazole, and 7 isolates (6.1%) had reduced susceptibility to vancomycin. These findings highlight the need for continuous surveillance of C. difficile RTs and antimicrobial susceptibility testing.",

author = "Adri{\'a}n Mart{\'i}nez-Mel{\'e}ndez and Laura Tijerina-Rodr{\'i}guez and Nathania Collins and Baines, {Simon D.} and Rayo Morfin-Otero and Adri{\'a}n Camacho-Ort{\'i}z and Licet Villarreal-Trevi{\~n}o and Elvira Garza-Gonz{\'a}lez",

note = "Funding Information: This work was funded by Consejo Nacional de Ciencia y Tecnolog{\'i}a (Grant 284042). Publisher Copyright: {\textcopyright} Copyright 2021, Mary Ann Liebert, Inc., publishers 2021.",

year = "2021",

month = dec,

doi = "10.1089/mdr.2020.0583",

language = "English",

volume = "27",

pages = "1672--1676",

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Martínez-Meléndez, A, Tijerina-Rodríguez, L, Collins, N, Baines, SD, Morfin-Otero, R, Camacho-Ortíz, A, Villarreal-Treviño, L & Garza-González, E 2021, 'Diversity of Circulating Clostridioides difficile Ribotypes in Mexico and Susceptibility to Fidaxomicin, Vancomycin, and Metronidazole', Microbial Drug Resistance, vol. 27, no. 12, pp. 1672-1676. https://doi.org/10.1089/mdr.2020.0583

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T1 - Diversity of Circulating Clostridioides difficile Ribotypes in Mexico and Susceptibility to Fidaxomicin, Vancomycin, and Metronidazole

AU - Martínez-Meléndez, Adrián

AU - Tijerina-Rodríguez, Laura

AU - Collins, Nathania

AU - Baines, Simon D.

AU - Morfin-Otero, Rayo

AU - Camacho-Ortíz, Adrián

AU - Villarreal-Treviño, Licet

AU - Garza-González, Elvira

PY - 2021/12

Y1 - 2021/12

N2 - In this study, we report the results of the epidemiological analysis of Clostridioides difficile ribotypes (RTs) and antimicrobial susceptibility testing. Most isolates were RT027, representing 73% (84/115) of isolates. No isolates with reduced susceptibility to fidaxomicin were found; however, 38 (33.04%) isolates had reduced susceptibility to metronidazole, and 7 isolates (6.1%) had reduced susceptibility to vancomycin. These findings highlight the need for continuous surveillance of C. difficile RTs and antimicrobial susceptibility testing.

AB - In this study, we report the results of the epidemiological analysis of Clostridioides difficile ribotypes (RTs) and antimicrobial susceptibility testing. Most isolates were RT027, representing 73% (84/115) of isolates. No isolates with reduced susceptibility to fidaxomicin were found; however, 38 (33.04%) isolates had reduced susceptibility to metronidazole, and 7 isolates (6.1%) had reduced susceptibility to vancomycin. These findings highlight the need for continuous surveillance of C. difficile RTs and antimicrobial susceptibility testing.

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Diversity of Circulating Clostridioides difficile Ribotypes in Mexico and Susceptibility to Fidaxomicin, Vancomycin, and Metronidazole

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Department of Biological and Environmental Sciences, School of Life and Medical Sciences, University of Hertfordshire, Hatfield, Hertfordshire, United Kingdom.

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Diversity of Circulating Clostridioides difficile Ribotypes in Mexico and Susceptibility to Fidaxomicin, Vancomycin, and Metronidazole

Abstract

Bibliographical note

All Science Journal Classification (ASJC) codes

Access to Document

Other files and links

Fingerprint

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Department of Biological and Environmental Sciences, School of Life and Medical Sciences, University of Hertfordshire, Hatfield, Hertfordshire, United Kingdom.

Cite this