TY - JOUR
T1 - Cutaneous graft-versus-host disease after hematopoietic stem cell transplant - A review
AU - Villarreal-Villarreal, Cesar Daniel
AU - Salas-Alanis, Julio Cesar
AU - Jaime-Pérez, Jose Carlos
AU - Ocampo-Candiani, Jorge
PY - 2016/7/22
Y1 - 2016/7/22
N2 - Graft-versus-host disease (GVHD) is a major complication of allogeneic hematopoietic stem cell transplants (allo-HSCT) associated with significant morbidity and mortality. The earliest and most common manifestation is cutaneous graft-versus-host disease. This review focuses on the pathophysiology, clinical features, prevention and treatment of cutaneous graft-versus-host disease. We discuss various insights into the disease’s mechanisms and the different treatments for acute and chronic skin graft-versus-host disease.
AB - Graft-versus-host disease (GVHD) is a major complication of allogeneic hematopoietic stem cell transplants (allo-HSCT) associated with significant morbidity and mortality. The earliest and most common manifestation is cutaneous graft-versus-host disease. This review focuses on the pathophysiology, clinical features, prevention and treatment of cutaneous graft-versus-host disease. We discuss various insights into the disease’s mechanisms and the different treatments for acute and chronic skin graft-versus-host disease.
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U2 - 10.1590/abd1806-4841.20164180
DO - 10.1590/abd1806-4841.20164180
M3 - Review article
C2 - 27438202
SN - 0365-0596
VL - 91
SP - 336
EP - 343
JO - Anais Brasileiros de Dermatologia
JF - Anais Brasileiros de Dermatologia
IS - 3
ER -