Clinical and molecular delineation of duplication 9p24.3q21.11 in a patient with psychotic behavior

Lizeth Martínez-Jacobo, Rocío Ortíz-López, Alfredo Rizo-Méndez, Viridiana García-Molina, Sandra K. Santuario-Facio, Fernando Rivas, Augusto Rojas-Martínez

Research output: Contribution to journalArticlepeer-review

6 Citations (Scopus)

Abstract

This article describes a 19-year-old female with mild facial dysmorphism, asociality, decreased school performance, and psychotic behavior in whom the karyotype showed an extra-chromosomal marker characterized as 9p24.3-9q21.11 duplication by array-CGH. The 69. Mbp duplicated segment in this patient includes the critical 9p duplication syndrome region, the GLDC and C90RF72 genes associated with psychotic behavior and other conduct disorders, and a potential locus for autism.

Original languageEnglish
Pages (from-to)124-127
Number of pages4
JournalGene
Volume560
Issue number1
DOIs
Publication statusPublished - 10 Apr 2015
Externally publishedYes

Bibliographical note

Funding Information:
We would like to thank the patient's mother for their cooperation along this study. Lizeth Martínez-Jacobo is supported by a CONACYT (Mexico) scholarship.

Publisher Copyright:
© 2015 Elsevier B.V.

Copyright:
Copyright 2020 Elsevier B.V., All rights reserved.

All Science Journal Classification (ASJC) codes

  • Genetics

Fingerprint Dive into the research topics of 'Clinical and molecular delineation of duplication 9p24.3q21.11 in a patient with psychotic behavior'. Together they form a unique fingerprint.

Cite this