Clavispora lusitaniae: From a saprophytic yeast to an emergent pathogen

Olga C. Rojas*, Alexandra M. Montoya, Rogelio de J. Treviño-Rangel

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

Abstract

Clavispora lusitaniae has been isolated from different substrates, such as soil, water, fruit, vegetables, plants, and the gastrointestinal tract of animals and humans. However, its importance lies in being isolated from in invasive infections, particularly in pediatric patients with hematologic malignancies. It is an emerging nosocomial pathogen commonly associated with fatal prognosis in immunocompromised hosts. C. lusitaniae has attracted attention in the last decade because of resistance to amphotericin B, 5- flucytosine, and fluconazole. The adaptations of this yeast to the human host may contribute to its pathogenicity. Further study will be needed to understand C. lusitaniae's ability as a potential pathogen. This mini-review highlights the importance of the growing number of invasive disease cases caused by this yeast.

Original languageEnglish
Pages (from-to)1933-1938
Number of pages6
JournalFungal Biology
Volume128
Issue number5
DOIs
Publication statusPublished - Aug 2024

Bibliographical note

Publisher Copyright:
© 2024 British Mycological Society

All Science Journal Classification (ASJC) codes

  • Ecology, Evolution, Behavior and Systematics
  • Genetics
  • Infectious Diseases

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