TY - JOUR
T1 - Association between Mexican vaccination schemes and the duration of long COVID syndrome symptoms
AU - Rodriguez-Torres, Juan Francisco
AU - Romero-Ibarguengoitia, Maria Elena
AU - Garza-Silva, Arnulfo
AU - Rivera-Cavazos, Andrea
AU - Hurtado-Cabrera, Mauricio
AU - Kalife-Assad, Ricardo
AU - Villarreal-Parra, Diana Liz
AU - Loose-Esparza, Alejandro
AU - Gutierrez-Arias, Juan José
AU - Mata-Porras, Yaressi Guadalupe
AU - Ojeda-Salazar, Daniela Abigail
AU - Morales-Rodriguez, Devany Paola
AU - Sanz-Sánchez, Miguel Ángel
AU - Gonzalez-Cantú, Arnulfo
N1 - © 2025. The Author(s).
PY - 2025/2/12
Y1 - 2025/2/12
N2 - The COVID-19 pandemic had a profound global impact, characterized by a high fatality rate and the emergence of enduring consequences known as Long COVID. Our study sought to gauge the prevalence of Long COVID syndrome in northeastern Mexico, correlating it with patients' comorbidities and vaccination records. We carried out an observational cross-sectional approach, by administering a comprehensive questionnaire covering patients' medical history, demographics, vaccination status, COVID-related symptoms, their duration, and any treatment received. Our participant cohort included 804 patients, averaging 41.5 (SD 13.6) years in age, with 59.3% being women. Notably, 168 individuals (20.9%) met Long COVID criteria. Our analysis of COVID-19 long lasting compared vaccination schemes, unveiling a significant difference between vaccinated and unvaccinated groups (p = < 0.001). Through linear regression model, we found male gender (β = - 0.588, p < 0.001) and vaccination status (β = 0.221, p = 0.015) acted as protective factors against Long COVID symptom duration, while higher BMI was a risk factor (β = - 0.131, p = 0.026). We saw that the duration of Long COVID was different within vaccinated patients, and we did not find any association of comorbidities with an increase in the presence of symptoms. Even three years after the pandemic, a significant prevalence of Long COVID persists, and there is still a lack of standardized information and any possible treatment regarding this condition.
AB - The COVID-19 pandemic had a profound global impact, characterized by a high fatality rate and the emergence of enduring consequences known as Long COVID. Our study sought to gauge the prevalence of Long COVID syndrome in northeastern Mexico, correlating it with patients' comorbidities and vaccination records. We carried out an observational cross-sectional approach, by administering a comprehensive questionnaire covering patients' medical history, demographics, vaccination status, COVID-related symptoms, their duration, and any treatment received. Our participant cohort included 804 patients, averaging 41.5 (SD 13.6) years in age, with 59.3% being women. Notably, 168 individuals (20.9%) met Long COVID criteria. Our analysis of COVID-19 long lasting compared vaccination schemes, unveiling a significant difference between vaccinated and unvaccinated groups (p = < 0.001). Through linear regression model, we found male gender (β = - 0.588, p < 0.001) and vaccination status (β = 0.221, p = 0.015) acted as protective factors against Long COVID symptom duration, while higher BMI was a risk factor (β = - 0.131, p = 0.026). We saw that the duration of Long COVID was different within vaccinated patients, and we did not find any association of comorbidities with an increase in the presence of symptoms. Even three years after the pandemic, a significant prevalence of Long COVID persists, and there is still a lack of standardized information and any possible treatment regarding this condition.
U2 - 10.1038/s41598-024-59954-z
DO - 10.1038/s41598-024-59954-z
M3 - Article
C2 - 39939334
SN - 2045-2322
VL - 15
SP - 5301
JO - Scientific Reports
JF - Scientific Reports
IS - 1
ER -
