Anatomical, biomechanical and aberrometric corneal characteristics of patients with Marfan syndrome

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© 2014 Sociedad Mexicana de Oftalmología. Published by Masson Doyma México S.A. Objective: To know the anatomical (mean keratometry, central pachimetry), optic (corneal aberrations represented by Zernike polynomials) and biomechanical (corneal hysteresis, and corneal resistance factor) characteristics in patients with Marfan syndrome. Material and methods: Prospective, transversal and observational study. We study patients with confirmed diagnosis of Marfan syndrome. The anatomical and aberrometrical characteristics was measured with otating Scheimpflug Camera (Pentacam, Oculus) and the biomechanical characteristics with ocular response analyzer (Reichert). The ocular response analyzer measures was made 4 times and represented by his average. All the studies was made by the same examiner. Results: Twenty eyes of 10 patients with confirmed diagnosis of Marfan syndrome was studied. 60% was male with an average age of 24 ± 10.79 years (range, 11-39). Three eyes of 2 patients was aphakic because a spontaneous posterior lens dislocation, of the other 17 eyes 100% subluxation of the lens. Mean simK was 40.49 ± 1.54 D (range, 38.7-42.7) 80% had less than 42 D. Average central corneal thickness was 562 ± 37.23 μm (range 506-626 μm). All the patients had a patological aberration coefficient 1.55 ± 0.37 (range, 1.1-2.5). Corneal hysteresis was 9.13 ± 1.49 mmHg (range, 7.1-12) and corneal resistance factor 9.09 ± 2.41 mmHg (range, 4.8-13.6). Conclusions: In our studied group, the corneas of Marfan syndrome patients presents a flat corneas with a normal pachymetry and biomechanical properties but with a abnormal aberration coefficient values.
Original languageEnglish
Pages (from-to)93-97
Number of pages5
JournalRevista Mexicana de Oftalmologia
Publication statusPublished - 1 Jan 2015
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Ophthalmology

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