Rafael Baltazar Reyes León Cachón

PhD, Doctor en Ciencias

  • 97 Citations
  • 5 h-Index
20102019
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Research Output 2010 2019

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Article
2018

ACE, APOA5, and MTP Gene Polymorphisms Analysis in Relation to Triglyceride and Insulin Levels in Pediatric Patients

Carranza-González, L., León-Cachón, R. B. R., González-Zavala, M. A., Ríos-Ibarra, C., Morlett-Chávez, J., Sánchez-Domínguez, C., Cepeda-Nieto, A. & Salinas-Santander, M., 1 Feb 2018, In : Archives of Medical Research. 49, 2, p. 94-100 7 p.

Research output: Contribution to journalArticle

Triglycerides
Insulin
Pediatrics
Phenotype
Population

A novel method to detect the Mexican founder mutation BRCA1 ex9-12del associated with breast and ovarian cancer using quantitative polymerase chain reaction and TaqMan probes

Martínez-Treviño, D. A., León-Cachón, R. B. R., Villarreal-Garza, C., Méndez, D. A. Y., Aguilar-Martínez, E. & Barrera-Saldaña, H. A., 1 Aug 2018, In : Molecular Medicine Reports. 18, 2, p. 1531-1537 7 p.

Research output: Contribution to journalArticle

Polymerase chain reaction
Ovarian Neoplasms
Introns
Exons
Breast Neoplasms
1 Citation (Scopus)

Genotypic and phenotypic factors influencing drug response in Mexican patients with type 2 Diabetes Mellitus

Sanchez-Ibarra, H. E., Reyes-Cortes, L. M., Jiang, X. L., Luna-Aguirre, C. M., Aguirre-Trevino, D., Morales-Alvarado, I. A., Leon-Cachon, R. B., Lavalle-Gonzalez, F., Morcos, F. & Barrera-Saldaña, H. A., 6 Apr 2018, In : Frontiers in Pharmacology. 9, APR, 320.

Research output: Contribution to journalArticle

Hypoglycemic Agents
Type 2 Diabetes Mellitus
Pharmaceutical Preparations
Genotype
Biguanides
1 Citation (Scopus)

Infrared meibography and molecular assessment of p63 gene mutations in a Mexican patient with EEC syndrome

Garza-Leon, M., León-Cachón, R. B. R., Villafuerte-de la Cruz, R. & Martínez-Treviño, D. A., 1 Nov 2018, In : Archivos de la Sociedad Espanola de Oftalmologia. 93, 11, p. 562-566 5 p.

Research output: Contribution to journalArticle

Meibomian Glands
Mutation
Eyelids
Genes
Anodontia
2017
1 Citation (Scopus)

Effect of AGTR1 and BDKRB2 gene polymorphisms on atorvastatin metabolism in a Mexican population

Herrera-González, S., Martínez-Treviño, D. A., Aguirre-Garza, M., Gómez-Silva, M., Barrera-Saldaña, H. A. & León-Cachón, R. B. R., 1 Dec 2017, In : Biomedical Reports. p. 579-584 6 p.

Research output: Contribution to journalArticle

Polymorphism
Metabolism
Pharmacokinetics
Genes
Phenotype
5 Citations (Scopus)

Molecular identification of unusual Mycetoma agents isolated from patients in Venezuela

Rojas, O. C., León-Cachón, R. B. R., Moreno-Treviño, M. & González, G. M., 1 Feb 2017, In : Mycoses. 60, 2, p. 129-135 7 p.

Research output: Contribution to journalArticle

Mycetoma
Venezuela
Proxy
Nocardia
Madurella
8 Citations (Scopus)

Prediction of atorvastatin plasmatic concentrations in healthy volunteers using integrated pharmacogenetics sequencing

Cruz-Correa, O. F., León-Cachón, R. B. R., Barrera-Saldaña, H. A. & Soberón, X., 1 Jan 2017, In : Pharmacogenomics. p. 121-131 11 p.

Research output: Contribution to journalArticle

Pharmacogenetics
Area Under Curve
Healthy Volunteers
Genes
Medicine
2016
14 Citations (Scopus)

A pharmacogenetic pilot study reveals MTHFR, DRD3, and MDR1 polymorphisms as biomarker candidates for slow atorvastatin metabolizers

León-Cachón, R. B. R., Ascacio-Martínez, J. A., Gamino-Peña, M. E., Cerda-Flores, R. M., Meester, I., Gallardo-Blanco, H. L., Gómez-Silva, M., Piñeyro-Garza, E. & Barrera-Saldaña, H. A., 8 Feb 2016, In : BMC Cancer. 16, 1, 74.

Research output: Contribution to journalArticle

Biomarkers
Pharmacokinetics
Phenotype
Healthy Volunteers
Population
1 Citation (Scopus)

Assessment of biochemical parameters and characterization of TNFα -308G/A and PTPN22 +1858c/T gene polymorphisms in the risk of obesity in adolescents

Salinas-Santander, M. A., León-Cachón, R. B., Cepeda-Nieto, A. C., Sánchez-Domínguez, C. N., González-Zavala, M. A., Gallardo-Blanco, H. L., Esparza-González, S. C. & González-Madrazo, M. Á., 1 Jan 2016, In : Biomedical Reports. 4, 1, p. 107-111 5 p.

Research output: Contribution to journalArticle

Pediatric Obesity
Polymorphism
Tumor Necrosis Factor-alpha
Genes
Obesity

Efectos adversos de los antibióticos sobre la mitocondria y su asociación con variantes genéticas del ADN mitocondrial en población mexicana

Translated title of the contribution: Adverse effects of antibiotics on the mitochondria and their association with genetic variants of mitochondrial DNA in Mexican populationHerrera-González, S., García Tovar, L. E., Martínez-Treviño, D. A., Rojas, O. C. & León Cachón, R. B. R., 6 May 2016, In : Revista Mexicana de Ciencias Farmaceuticas. 46, 4, p. 15-24 10 p.

Research output: Contribution to journalArticle

Open Access
Mitochondrial DNA
Mitochondria
Anti-Bacterial Agents
Population
origen
3 Citations (Scopus)

Rapid Detection of the GSTM3 A/B Polymorphism Using Real-time PCR with TaqMan® Probes

Martínez-Treviño, D. A., Moreno-Treviño, M. G., Salinas-Santander, M., Wohn, L., Herrera-González, S., Aguirre-Garza, M., Rojas, O. C. & León-Cachón, R. B. R., 1 Feb 2016, In : Archives of Medical Research. 47, 2, p. 142-145 4 p.

Research output: Contribution to journalArticle

Real-Time Polymerase Chain Reaction
Glutathione Transferase
Phase II Metabolic Detoxication
Genotyping Techniques
Xenobiotics
2015
5 Citations (Scopus)

Phenotypic and molecular identification of Fonsecaea pedrosoi strains isolated from chromoblastomycosis patients in Mexico and Venezuela

Carolina Rojas, O., León-Cachón, R. B. R., Pérez-Maya, A. A., Aguirre-Garza, M., Moreno-Treviño, M. G. & González, G. M., 1 Jan 2015, In : Mycoses. 58, 5, p. 267-272 6 p.

Research output: Contribution to journalArticle

Chromoblastomycosis
Venezuela
Mexico
terbinafine
Ribosomal Spacer DNA
2014
2 Citations (Scopus)

Real-time PCR Detection of the Recessive Dystrophic Epidermolysis Bullosa-associated c.2470insG Mutation in Unrelated Mexican Families

Moreno-Treviño, M. G., León-Cachón, R. B. R., González-Salazar, F., Aguirre-Garza, M., Cerda-Flores, R. M., Meester, I. & Salas-Alanis, J. C., 1 Jan 2014, In : Archives of Medical Research. 45, 7, p. 596-599 4 p.

Research output: Contribution to journalArticle

Epidermolysis Bullosa Dystrophica
Real-Time Polymerase Chain Reaction
Mutation
Genotype
High-Throughput Screening Assays

Relationship of Mitochondrial DNA Haplogroups with Complex Diseases

Urzúa Traslaviña, C. G., Moreno Treviño, M. G., Martínez-Treviño, D. A., Barrera-Saldaña, H. & León Cachón, R. B. R., 16 Dec 2014, In : Journal of Genetics and Genome Research. 1, 2, p. 1-5 6 p.

Research output: Contribution to journalArticle

Open Access
Mitochondrial DNA
Mitochondria
Metabolic Diseases
Eukaryota
Research
2012
2 Citations (Scopus)

Evaluating SKI as a candidate gene for non-syndromic cleft lip with or without cleft palate

Mangold, E., Reutter, H., León-Cachón, R. B. R., Ludwig, K. U., Herms, S., Chacón-Camacho, Ó., Ortiz-López, R., Paredes-Zenteno, M., Arizpe-Cantú, A., Muñoz-Jiménez, S. G., Nowak, S., Kramer, F. J., Wienker, T. F., Nöthen, M. M., Knapp, M. & Rojas-Martínez, A., 1 Oct 2012, In : European Journal of Oral Sciences. p. 373-377 5 p.

Research output: Contribution to journalArticle

Cleft Lip
Cleft Palate
Genes
Population
Philippines
2010
41 Citations (Scopus)

Genetic risk factors for nonsyndromic cleft lip with or without cleft palate in a mesoamerican population: Evidence for IRF6 and variants at 8q24 and 10q25

Rojas-Martinez, A., Reutter, H., Chacon-Camacho, O., Leon-Cachon, R. B. R., Munoz-Jimenez, S. G., Nowak, S., Becker, J., Herberz, R., Ludwig, K. U., Paredes-Zenteno, M., Arizpe-Cantú, A., Raeder, S., Herms, S., Ortiz-Lopez, R., Knapp, M., Hoffmann, P., Nöthen, M. M. & Mangold, E., 1 Jan 2010, In : Birth Defects Research Part A - Clinical and Molecular Teratology. p. 535-537 3 p.

Research output: Contribution to journalArticle

Cleft Lip
Cleft Palate
Population
Genome-Wide Association Study
Homozygote